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5MH5

D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with 2-keto-hexanoic acid and NADP+ (1.4 A resolution)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
D-2-hydroxyacid dehydrogenasepolymer30833368.02UniProt (Q2VEQ7)Haloferax mediterranei ATCC 33500D2-HDH,D-specific 2-hydroxyacid dehydrogenase
2C, D, E, F, G...
(A, B)
MAGNESIUM IONnon-polymer24.321Chemie (MG)
PubChem (888)
3AA, O
(B, A)
2-Ketohexanoic acidnon-polymer130.12Chemie (7N5)
PubChem (159664)
4BA, P
(B, A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.42Chemie (NAP)
PubChem (5885)
PubChem (46936685)
PubChem (71717786)
PubChem (4412)
PubChem (90473931)
PubChem (91972139)
PubChem (145946263)
PubChem (153311489)
PubChem (174001641)
PubChem (165382010)
5CA, Q
(B, A)
SULFATE IONnon-polymer96.12Chemie (SO4)
6DA, EA
(A, B)
waterwater18.0676Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight66736.0
Non-Polymers*Number of molecules27
Total formula weight2449.6
All*Total formula weight69185.6
*Water molecules are not included.

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PDB entries from 2026-05-13

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