Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0031406 | molecular_function | carboxylic acid binding |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070402 | molecular_function | NADPH binding |
| A | 0070404 | molecular_function | NADH binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0031406 | molecular_function | carboxylic acid binding |
| B | 0051287 | molecular_function | NAD binding |
| B | 0070402 | molecular_function | NADPH binding |
| B | 0070404 | molecular_function | NADH binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 401 |
| Chain | Residue |
| A | HOH659 |
| A | HOH734 |
| B | GLU211 |
| B | HOH557 |
| B | HOH584 |
| B | HOH733 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | HOH806 |
| A | HOH814 |
| A | HOH827 |
| A | HOH562 |
| A | HOH569 |
| A | HOH582 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 403 |
| Chain | Residue |
| A | HOH546 |
| A | HOH710 |
| A | HOH747 |
| A | HOH794 |
| A | HOH811 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 404 |
| Chain | Residue |
| A | THR132 |
| A | ALA134 |
| A | HOH594 |
| A | HOH630 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 405 |
| Chain | Residue |
| A | GLU202 |
| A | HOH631 |
| A | HOH659 |
| B | PRO180 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 406 |
| Chain | Residue |
| A | HOH537 |
| A | HOH781 |
| A | HOH818 |
| A | HOH829 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 407 |
| Chain | Residue |
| A | GLU302 |
| A | HOH502 |
| A | HOH722 |
| A | HOH762 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 408 |
| Chain | Residue |
| A | ASP172 |
| A | HOH538 |
| A | HOH676 |
| A | HOH799 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 409 |
| Chain | Residue |
| A | GLU211 |
| A | HOH540 |
| A | HOH613 |
| B | HOH565 |
| B | HOH657 |
| B | HOH762 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 410 |
| Chain | Residue |
| A | PHE212 |
| A | GLU213 |
| A | MET215 |
| A | ASP243 |
| A | HOH745 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 416 |
| Chain | Residue |
| A | HIS120 |
| A | HOH530 |
| A | HOH713 |
| B | ASP265 |
| B | HOH532 |
| B | HOH663 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 411 |
| Chain | Residue |
| A | HOH554 |
| A | HOH757 |
| A | HOH776 |
| A | HOH797 |
| A | HOH802 |
| A | HOH828 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 412 |
| Chain | Residue |
| A | HOH528 |
| A | HOH584 |
| A | HOH615 |
| A | HOH826 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue 7N5 A 413 |
| Chain | Residue |
| A | ARG66 |
| A | ALA67 |
| A | GLY68 |
| A | HIS91 |
| A | ARG226 |
| A | HIS274 |
| A | ALA277 |
| A | NAP414 |
| site_id | AD6 |
| Number of Residues | 39 |
| Details | binding site for residue NAP A 414 |
| Chain | Residue |
| A | HOH564 |
| A | HOH569 |
| A | HOH574 |
| A | HOH582 |
| A | HOH624 |
| A | HOH643 |
| A | HOH646 |
| A | HOH671 |
| A | HOH679 |
| A | HOH694 |
| A | HOH711 |
| A | HOH727 |
| A | ALA67 |
| A | GLY68 |
| A | THR88 |
| A | GLY142 |
| A | LEU143 |
| A | GLY144 |
| A | THR145 |
| A | LEU146 |
| A | ARG165 |
| A | ARG166 |
| A | SER167 |
| A | PRO180 |
| A | ALA196 |
| A | THR197 |
| A | PRO198 |
| A | THR203 |
| A | VAL224 |
| A | ALA225 |
| A | ARG226 |
| A | ASP250 |
| A | HIS274 |
| A | SER276 |
| A | 7N5413 |
| A | HOH505 |
| A | HOH548 |
| A | HOH560 |
| A | HOH562 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 415 |
| Chain | Residue |
| A | ARG148 |
| A | ARG165 |
| A | HOH517 |
| A | HOH531 |
| A | HOH561 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 402 |
| Chain | Residue |
| B | HOH548 |
| B | HOH602 |
| B | HOH631 |
| B | HOH808 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 403 |
| Chain | Residue |
| A | ASP201 |
| B | THR214 |
| B | HOH526 |
| B | HOH651 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 404 |
| Chain | Residue |
| B | VAL177 |
| B | HOH624 |
| B | HOH625 |
| B | HOH728 |
| B | HOH782 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 401 |
| Chain | Residue |
| A | ASP265 |
| A | HOH645 |
| A | HOH703 |
| B | HIS120 |
| B | HOH516 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 405 |
| Chain | Residue |
| B | PHE212 |
| B | GLU213 |
| B | MET215 |
| B | ASP243 |
| B | HOH768 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 406 |
| Chain | Residue |
| B | THR132 |
| B | ALA134 |
| B | HOH571 |
| B | HOH724 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 407 |
| Chain | Residue |
| B | HOH511 |
| B | HOH535 |
| B | HOH586 |
| B | HOH677 |
| B | HOH778 |
| B | HOH821 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 408 |
| Chain | Residue |
| B | HOH506 |
| B | HOH524 |
| B | HOH701 |
| B | HOH804 |
| B | HOH820 |
| B | HOH823 |
| site_id | AE7 |
| Number of Residues | 9 |
| Details | binding site for residue 7N5 B 409 |
| Chain | Residue |
| B | ARG66 |
| B | ALA67 |
| B | GLY68 |
| B | HIS91 |
| B | ARG226 |
| B | HIS274 |
| B | TYR282 |
| B | NAP410 |
| B | HOH514 |
| site_id | AE8 |
| Number of Residues | 39 |
| Details | binding site for residue NAP B 410 |
| Chain | Residue |
| B | ALA67 |
| B | GLY68 |
| B | THR88 |
| B | LEU143 |
| B | GLY144 |
| B | THR145 |
| B | LEU146 |
| B | ARG165 |
| B | ARG166 |
| B | SER167 |
| B | PRO180 |
| B | ALA196 |
| B | THR197 |
| B | PRO198 |
| B | THR203 |
| B | VAL224 |
| B | ALA225 |
| B | ARG226 |
| B | ASP250 |
| B | VAL251 |
| B | HIS274 |
| B | SER276 |
| B | 7N5409 |
| B | HOH501 |
| B | HOH548 |
| B | HOH560 |
| B | HOH587 |
| B | HOH590 |
| B | HOH602 |
| B | HOH612 |
| B | HOH631 |
| B | HOH650 |
| B | HOH653 |
| B | HOH655 |
| B | HOH664 |
| B | HOH706 |
| B | HOH721 |
| B | HOH736 |
| B | HOH740 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 411 |
| Chain | Residue |
| B | ARG148 |
| B | ARG165 |
| B | HOH505 |
| B | HOH570 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P0A9T0","evidenceCode":"ECO:0000250"}]} |
