6IZK
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![BU of 6izk by Molmil](/molmil-images/mine/6izk) | Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus | Descriptor: | CHLORIDE ION, IMIDAZOLE, L(+)-TARTARIC ACID, ... | Authors: | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | Deposit date: | 2018-12-19 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus To Be Published
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6VBK
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![BU of 6vbk by Molmil](/molmil-images/mine/6vbk) | Crystal structure of N-terminal domain of Mycobacterium tuberculosis complex Lon protease | Descriptor: | GLYCEROL, Lon211 | Authors: | Bi, F.K, Chen, C, Chen, X.Y, Guo, C.Y, Lin, D.H. | Deposit date: | 2019-12-19 | Release date: | 2020-12-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex. Protein Sci., 28, 2019
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7QZQ
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![BU of 7qzq by Molmil](/molmil-images/mine/7qzq) | Crystal structure of the kelch domain of human KBTBD12 | Descriptor: | 1,2-ETHANEDIOL, Kelch repeat and BTB domain-containing protein 12, SODIUM ION | Authors: | Manning, C.E, Chen, Z, Chen, X, Bradshaw, W.J, Bakshi, S, Mckinley, G, Chalk, R, Burgess-Brown, N, von Delft, F, Bullock, A.N. | Deposit date: | 2022-01-31 | Release date: | 2022-05-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structure of the kelch domain of human KBTBD12 To Be Published
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4AY9
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![BU of 4ay9 by Molmil](/molmil-images/mine/4ay9) | Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLLICLE-STIMULATING HORMONE RECEPTOR, FOLLITROPIN SUBUNIT BETA, ... | Authors: | Jiang, X, Liu, H, Chen, X, He, X. | Deposit date: | 2012-06-19 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of Follicle-Stimulating Hormone in Complex with the Entire Ectodomain of its Receptor. Proc.Natl.Acad.Sci.USA, 109, 2012
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8Z1E
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![BU of 8z1e by Molmil](/molmil-images/mine/8z1e) | A homotrimeric GPCR architecture of the human cytomegalovirus (UL78) revealed by cryo-EM | Descriptor: | Uncharacterized protein UL78 | Authors: | Chen, Y, Li, Y, Zhou, Q, Cong, Z, Lin, S, Yan, J, Chen, X, Yang, D, Ying, T, Wang, M.-W. | Deposit date: | 2024-04-11 | Release date: | 2024-05-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | A homotrimeric GPCR architecture of the human cytomegalovirus revealed by cryo-EM. Cell Discov, 10, 2024
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6IHK
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![BU of 6ihk by Molmil](/molmil-images/mine/6ihk) | Structure of MMPA CoA ligase in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AMP-binding domain protein | Authors: | Shao, X, Cao, H.Y, Wang, P, Li, C.Y, Zhao, F, Peng, M, Chen, X.L, Zhang, Y.Z. | Deposit date: | 2018-09-30 | Release date: | 2019-07-03 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria. Mol.Microbiol., 111, 2019
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6IJB
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![BU of 6ijb by Molmil](/molmil-images/mine/6ijb) | Structure of 3-methylmercaptopropionate CoA ligase mutant K523A in complex with AMP and MMPA | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-(methylsulfanyl)propanoic acid, ADENOSINE MONOPHOSPHATE, ... | Authors: | Shao, X, Cao, H.Y, Wang, P, Li, C.Y, Zhao, F, Peng, M, Chen, X.L, Zhang, Y.Z. | Deposit date: | 2018-10-09 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.111 Å) | Cite: | Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria. Mol.Microbiol., 111, 2019
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6IHI
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![BU of 6ihi by Molmil](/molmil-images/mine/6ihi) | Crystal structure of RasADH 3B3/I91V from Ralstonia.sp in complex with NADPH and A6O | Descriptor: | (2R,3S)-2-ethyl-2-[(2E)-2-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]-3-oxidanyl-cyclopentan-1-one, Alclohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhang, H.L, Chen, X, Liu, W.D, Wu, Q.Q, Zhu, D.M. | Deposit date: | 2018-09-30 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Efficient reductive desymmetrization of bulky 1,3-cyclodiketones enabled by structure-guided directed evolution of a carbonyl reductase. Nat Catal, 2, 2019
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8CIE
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![BU of 8cie by Molmil](/molmil-images/mine/8cie) | Crystal structure of the human CDKL5 kinase domain with compound YL-354 | Descriptor: | 4-[[3,5-bis(fluoranyl)phenyl]carbonylamino]-~{N}-piperidin-4-yl-1~{H}-pyrazole-3-carboxamide, Cyclin-dependent kinase-like 5, SULFATE ION | Authors: | Richardson, W, Chen, X, Newman, J.A, Bakshi, S, Lakshminarayana, B, Brooke, L, Bullock, A.N. | Deposit date: | 2023-02-09 | Release date: | 2023-06-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. Acs Chem Neurosci, 14, 2023
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1KYJ
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![BU of 1kyj by Molmil](/molmil-images/mine/1kyj) | Tumor Associated Mucin Motif from CD43 protein | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Leukosialin (CD43) fragment | Authors: | Coltart, D.M, Williams, L.J, Glunz, P.W, Sames, D, Kuduk, S.D, Schwarz, J.B, Chen, X.-T, Royyuru, A.K, Danishefsky, S.D, Live, D.H. | Deposit date: | 2002-02-04 | Release date: | 2002-02-20 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | Principles of Mucin Architecture: Structural Studies on Synthetic Glycopeptides Bearing Clustered Mono-, Di-, Tri-, and Hexasaccharide Glycodomains J.Am.Chem.Soc., 124, 2002
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4RZM
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![BU of 4rzm by Molmil](/molmil-images/mine/4rzm) | Crystal structure of the Lsd19-lasalocid A complex | Descriptor: | CHLORIDE ION, Epoxide hydrolase LasB, FORMIC ACID, ... | Authors: | Mathews, I.I, Hotta, K, Chen, X, Kim, C.-Y. | Deposit date: | 2014-12-22 | Release date: | 2015-01-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis. J.Am.Chem.Soc., 137, 2015
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4XKL
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![BU of 4xkl by Molmil](/molmil-images/mine/4xkl) | Crystal structure of NDP52 ZF2 in complex with mono-ubiquitin | Descriptor: | ACETATE ION, Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL, ... | Authors: | Xie, X, Li, F, Wang, Y, Lin, Z, Chen, X, Liu, J, Pan, L. | Deposit date: | 2015-01-12 | Release date: | 2015-11-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2 Autophagy, 11, 2015
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6X91
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![BU of 6x91 by Molmil](/molmil-images/mine/6x91) | Crystal structure of MBP-fused human APOBEC1 | Descriptor: | CACODYLATE ION, Maltodextrin-binding protein, C->U-editing enzyme APOBEC-1 chimera, ... | Authors: | Wolfe, A.D, Li, S.-X, Chen, X.S. | Deposit date: | 2020-06-02 | Release date: | 2020-12-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.51 Å) | Cite: | The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity. NAR Cancer, 2, 2020
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5GWZ
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![BU of 5gwz by Molmil](/molmil-images/mine/5gwz) | The structure of Porcine epidemic diarrhea virus main protease in complex with an inhibitor | Descriptor: | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, PEDV main protease | Authors: | Wang, F, Chen, C, Yang, K, Liu, X, Liu, H, Xu, Y, Chen, X, Liu, X, Cai, Y, Yang, H. | Deposit date: | 2016-09-14 | Release date: | 2017-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus J. Med. Chem., 60, 2017
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7SH1
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![BU of 7sh1 by Molmil](/molmil-images/mine/7sh1) | Class II UvrA protein - Ecm16 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Excinuclease ABC subunit UvrA, ... | Authors: | Grade, P, Erlandson, A, Ullah, A, Mathews, I.I, Chen, X, Kim, C.-Y, Mera, P.E. | Deposit date: | 2021-10-07 | Release date: | 2022-10-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural and functional analyses of the echinomycin resistance conferring protein Ecm16 from Streptomyces lasalocidi. Sci Rep, 13, 2023
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2PFD
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![BU of 2pfd by Molmil](/molmil-images/mine/2pfd) | Anisotropically refined structure of FTCD | Descriptor: | Formimidoyltransferase-cyclodeaminase | Authors: | Poon, B.K, Chen, X, Lu, M, Quiocho, F.A, Wang, Q, Ma, J. | Deposit date: | 2007-04-04 | Release date: | 2007-04-24 | Last modified: | 2011-08-10 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Anisotropically refined structure of FTCD To be Published
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8X0X
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![BU of 8x0x by Molmil](/molmil-images/mine/8x0x) | Crystal structure of JE-5C in complex with SARS-CoV-2 RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of JE-5C Fab, Light chain of JE-5C Fab, ... | Authors: | Mohapatra, A, Chen, X. | Deposit date: | 2023-11-06 | Release date: | 2024-06-05 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine. Plos Pathog., 20, 2024
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8X0Y
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![BU of 8x0y by Molmil](/molmil-images/mine/8x0y) | Crystal structure of JM-1A in complex with SARS-CoV-2 RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heavy chain of JM-1A Fab, ... | Authors: | Mohapatra, A, Chen, X. | Deposit date: | 2023-11-06 | Release date: | 2024-06-05 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine. Plos Pathog., 20, 2024
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5X07
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![BU of 5x07 by Molmil](/molmil-images/mine/5x07) | Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site | Descriptor: | DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta | Authors: | Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y. | Deposit date: | 2017-01-20 | Release date: | 2017-08-16 | Last modified: | 2017-09-27 | Method: | X-RAY DIFFRACTION (2.796 Å) | Cite: | Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site Biochemistry, 56, 2017
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7RR5
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![BU of 7rr5 by Molmil](/molmil-images/mine/7rr5) | Structure of ribosomal complex bound with Rbg1/Tma46 | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... | Authors: | Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H. | Deposit date: | 2021-08-09 | Release date: | 2021-11-10 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells. Cell Rep, 37, 2021
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7SGL
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![BU of 7sgl by Molmil](/molmil-images/mine/7sgl) | DNA-PK complex of DNA end processing | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ... | Authors: | Liu, L, Li, J, Chen, X, Yang, W, Gellert, M. | Deposit date: | 2021-10-06 | Release date: | 2022-01-12 | Last modified: | 2022-01-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends. Mol.Cell, 82, 2022
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8YRO
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![BU of 8yro by Molmil](/molmil-images/mine/8yro) | SARS-CoV-2 Delta Spike in complex with JL-8C | Descriptor: | JL-8C Heavy Chain, JL-8C Light Chain, Spike glycoprotein | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2024-03-21 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine. Plos Pathog., 20, 2024
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8YRP
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![BU of 8yrp by Molmil](/molmil-images/mine/8yrp) | SARS-CoV-2 Delta Spike in complex with JM-1A | Descriptor: | JM-1A Heavy Chain, JM-1A Light Chain, Spike glycoprotein | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2024-03-21 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine. Plos Pathog., 20, 2024
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1LTL
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![BU of 1ltl by Molmil](/molmil-images/mine/1ltl) | THE DODECAMER STRUCTURE OF MCM FROM ARCHAEAL M. THERMOAUTOTROPHICUM | Descriptor: | DNA replication initiator (Cdc21/Cdc54), ZINC ION | Authors: | Fletcher, R.J, Bishop, B.E, Leon, R.P, Sclafani, R.A, Ogata, C.M, Chen, X.S. | Deposit date: | 2002-05-20 | Release date: | 2003-05-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Structure and function of MCM from archaeal M. Thermoautotrophicum Nat.Struct.Biol., 10, 2003
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7RSL
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![BU of 7rsl by Molmil](/molmil-images/mine/7rsl) | Seipin forms a flexible cage at lipid droplet formation sites | Descriptor: | Seipin | Authors: | Arlt, H, Sui, X, Folger, B, Adams, C, Chen, X, Remme, R, Hamprecht, F.A, DiMaio, F, Liao, M, Goodman, J.M, Farese Jr, R.V, Walther, T.C. | Deposit date: | 2021-08-11 | Release date: | 2022-02-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Seipin forms a flexible cage at lipid droplet formation sites. Nat.Struct.Mol.Biol., 29, 2022
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