4RZM

Crystal structure of the Lsd19-lasalocid A complex

Summary for 4RZM

Entry DOI	10.2210/pdb4rzm/pdb
Related	3RGA
Descriptor	Epoxide hydrolase LasB, Lasalocid A, GLYCEROL, ... (7 entities in total)
Functional Keywords	ntf2-like fold, epoxide-opening cyclic ether formation, isomerization, isomerase
Biological source	Streptomyces lasaliensis
Total number of polymer chains	2
Total formula weight	62920.04
Authors	Mathews, I.I.,Hotta, K.,Chen, X.,Kim, C.-Y. (deposition date: 2014-12-22, release date: 2015-01-21, Last modification date: 2023-09-20)
Primary citation	Wong, F.T.,Hotta, K.,Chen, X.,Fang, M.,Watanabe, K.,Kim, C.Y. Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis. J.Am.Chem.Soc., 137:86-89, 2015 Cited by PubMed: 25535803 DOI: 10.1021/ja511374k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation