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7SGL

DNA-PK complex of DNA end processing

Summary for 7SGL
Entry DOI10.2210/pdb7sgl/pdb
EMDB information25113
DescriptorDNA-dependent protein kinase catalytic subunit, X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, ... (9 entities in total)
Functional Keywordsendonuclease, kinase, complex, dna binding protein, transferase, dna binding protein-dna complex, dna binding protein/dna
Biological sourceHomo sapiens (Human)
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Total number of polymer chains6
Total formula weight737062.08
Authors
Liu, L.,Li, J.,Chen, X.,Yang, W.,Gellert, M. (deposition date: 2021-10-06, release date: 2022-01-12, Last modification date: 2022-01-19)
Primary citationLiu, L.,Chen, X.,Li, J.,Wang, H.,Buehl, C.J.,Goff, N.J.,Meek, K.,Yang, W.,Gellert, M.
Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Mol.Cell, 82:177-, 2022
Cited by
PubMed: 34936881
DOI: 10.1016/j.molcel.2021.11.025
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3 Å)
Structure validation

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