7SGL
DNA-PK complex of DNA end processing
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-dependent protein kinase catalytic subunit | polymer | 4128 | 469993.0 | 1 | UniProt (P78527) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) | Homo sapiens (Human) | DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460 |
| 2 | B (B) | X-ray repair cross-complementing protein 6 | polymer | 612 | 70198.3 | 1 | UniProt (P12956) Pfam (PF02037) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) | Homo sapiens (Human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 3 | C (C) | X-ray repair cross-complementing protein 5 | polymer | 732 | 82812.4 | 1 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785) | Homo sapiens (Human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 4 | D (D) | Protein artemis | polymer | 701 | 79479.4 | 1 | UniProt (Q96SD1) Pfam (PF07522) | Homo sapiens (Human) | DNA cross-link repair 1C protein,Protein A-SCID,SNM1 homolog C,hSNM1C,SNM1-like protein |
| 5 | E, F (E, F) | Hairpin_1 | polymer | 54 | 16636.7 | 2 | synthetic construct | ||
| 6 | G, J, K (A, D) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 7 | H (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 8 | I (B) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 9 | L (D) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
B: 1 - 609 (UniProt: P12956)
D: 1 - 692 (UniProt: Q96SD1)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Val 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 693 | - | expression tag |
| Ala 694 | - | expression tag |
| Ala 695 | - | expression tag |
| Leu 696 | - | expression tag |
| Glu 697 | - | expression tag |
| Val 698 | - | expression tag |
| Leu 699 | - | expression tag |
| Phe 700 | - | expression tag |
| Gln 701 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 735756.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1305.5 | |
| All* | Total formula weight | 737062.1 |
