6IJB

Structure of 3-methylmercaptopropionate CoA ligase mutant K523A in complex with AMP and MMPA

Summary for 6IJB

• Entry DOI: 10.2210/pdb6ijb/pdb
• Descriptor: AMP-binding domain protein, ADENOSINE MONOPHOSPHATE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• Functional Keywords: coa ligase, atp dependent, comformational change, ligase
• Biological source: Ruegeria lacuscaerulensis (strain DSM 11314 / KCTC 2953 / ITI-1157) (Silicibacter lacuscaerulensis)
• Total number of polymer chains: 2
• Total formula weight: 119564.47

Authors

Shao, X.,Cao, H.Y.,Wang, P.,Li, C.Y.,Zhao, F.,Peng, M.,Chen, X.L.,Zhang, Y.Z. (deposition date: 2018-10-09, release date: 2019-07-03, Last modification date: 2023-11-22)

• Primary citation: Shao, X.,Cao, H.Y.,Zhao, F.,Peng, M.,Wang, P.,Li, C.Y.,Shi, W.L.,Wei, T.D.,Yuan, Z.,Zhang, X.H.,Chen, X.L.,Todd, J.D.,Zhang, Y.Z.; Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria.; Mol.Microbiol., 111:1057-1073, 2019; PubMed: 30677184; DOI: 10.1111/mmi.14211

Experimental method

X-RAY DIFFRACTION (2.111 Å)