5ZZ8
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![BU of 5zz8 by Molmil](/molmil-images/mine/5zz8) | Structure of the Herpes simplex virus type 2 C-capsid with capsid-vertex-specific component | Descriptor: | Major capsid protein, UL17, UL25, ... | Authors: | Wang, J.L, Yuan, S, Zhu, D.J, Tang, H, Wang, N, Chen, W.Y, Gao, Q, Li, Y.H, Wang, J.Z, Liu, H.R, Zhang, X.Z, Rao, Z.H, Wang, X.X. | Deposit date: | 2018-05-31 | Release date: | 2018-10-10 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component. Nat Commun, 9, 2018
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8HPS
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![BU of 8hps by Molmil](/molmil-images/mine/8hps) | LpqY-SugABC in state 5 | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | Deposit date: | 2022-12-12 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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7Y4F
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![BU of 7y4f by Molmil](/molmil-images/mine/7y4f) | bacterial DPP4 | Descriptor: | Dipeptidyl peptidase IV | Authors: | Hang, J, Jiang, C, Wang, K, Zhang, Z, Guo, F, Liu, J, Wang, G, Lei, X, Gonzalez, F, Qiao, J. | Deposit date: | 2022-06-14 | Release date: | 2023-06-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.918 Å) | Cite: | Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target. Science, 381, 2023
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7Y4G
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![BU of 7y4g by Molmil](/molmil-images/mine/7y4g) | sit-bound btDPP4 | Descriptor: | (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-A MINE, btDPP4 | Authors: | Hang, J, Jiang, C, Wang, K, Zhang, Z, Guo, F, Liu, J, Wang, G, Lei, X, Gonzalez, F, Qiao, J. | Deposit date: | 2022-06-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target. Science, 381, 2023
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8HPR
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![BU of 8hpr by Molmil](/molmil-images/mine/8hpr) | LpqY-SugABC in state 4 | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | Deposit date: | 2022-12-12 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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5Z9Y
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![BU of 5z9y by Molmil](/molmil-images/mine/5z9y) | Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP | Descriptor: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase | Authors: | Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y. | Deposit date: | 2018-02-05 | Release date: | 2018-04-11 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG). Biochem. Biophys. Res. Commun., 497, 2018
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2ID8
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![BU of 2id8 by Molmil](/molmil-images/mine/2id8) | Crystal structure of Proteinase K | Descriptor: | (S)-(2,3-DIHYDROXYPROPOXY)TRIHYDROXYBORATE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Wang, J, Dauter, M, Dauter, Z. | Deposit date: | 2006-09-14 | Release date: | 2006-10-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | What can be done with a good crystal and an accurate beamline? Acta Crystallogr.,Sect.D, 62, 2006
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8HPM
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![BU of 8hpm by Molmil](/molmil-images/mine/8hpm) | LpqY-SugABC in state 2 | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | Deposit date: | 2022-12-12 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPN
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![BU of 8hpn by Molmil](/molmil-images/mine/8hpn) | LpqY-SugABC in state 3 | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | Deposit date: | 2022-12-12 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (4.55 Å) | Cite: | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPL
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![BU of 8hpl by Molmil](/molmil-images/mine/8hpl) | LpqY-SugABC in state 1 | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | Deposit date: | 2022-12-12 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (4.29 Å) | Cite: | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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7N0H
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![BU of 7n0h by Molmil](/molmil-images/mine/7n0h) | CryoEM structure of SARS-CoV-2 spike protein (S-6P, 2-up) in complex with sybodies (Sb45) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Jiang, J, Huang, R, Margulies, D. | Deposit date: | 2021-05-25 | Release date: | 2021-06-02 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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7N0G
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![BU of 7n0g by Molmil](/molmil-images/mine/7n0g) | CryoEm structure of SARS-CoV-2 spike protein (S-6P, 1-up) in complex with sybodies (Sb45) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Jiang, J, Huang, R, Margulies, D. | Deposit date: | 2021-05-25 | Release date: | 2021-06-02 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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8FY5
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![BU of 8fy5 by Molmil](/molmil-images/mine/8fy5) | Human TMEM175-LAMP1 full-length complex | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1 | Authors: | Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X. | Deposit date: | 2023-01-25 | Release date: | 2023-06-28 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. Mol.Cell, 83, 2023
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8FYF
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![BU of 8fyf by Molmil](/molmil-images/mine/8fyf) | Human TMEM175-LAMP1 transmembrane domain only complex | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1 | Authors: | Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X. | Deposit date: | 2023-01-26 | Release date: | 2023-06-28 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. Mol.Cell, 83, 2023
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7LGG
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![BU of 7lgg by Molmil](/molmil-images/mine/7lgg) | |
7LGH
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![BU of 7lgh by Molmil](/molmil-images/mine/7lgh) | |
7LGF
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![BU of 7lgf by Molmil](/molmil-images/mine/7lgf) | |
7LGE
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![BU of 7lge by Molmil](/molmil-images/mine/7lge) | |
7LHD
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![BU of 7lhd by Molmil](/molmil-images/mine/7lhd) | The complete model of phage Qbeta virion | Descriptor: | Capsid protein, Genomic RNA, Maturation protein A2 | Authors: | Chang, J.Y, Zhang, J. | Deposit date: | 2021-01-22 | Release date: | 2022-01-26 | Last modified: | 2022-03-09 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural Assembly of Q beta Virion and Its Diverse Forms of Virus-like Particles. Viruses, 14, 2022
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4DNC
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![BU of 4dnc by Molmil](/molmil-images/mine/4dnc) | Crystal structure of human MOF in complex with MSL1 | Descriptor: | Histone acetyltransferase KAT8, Male-specific lethal 1 homolog, ZINC ION | Authors: | Huang, J, Lei, M. | Deposit date: | 2012-02-08 | Release date: | 2012-07-25 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural insight into the regulation of MOF in the male-specific lethal complex and the non-specific lethal complex. Cell Res., 22, 2012
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3STA
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![BU of 3sta by Molmil](/molmil-images/mine/3sta) | Crystal structure of ClpP in tetradecameric form from Staphylococcus aureus | Descriptor: | ATP-dependent Clp protease proteolytic subunit | Authors: | Zhang, J, Ye, F, Lan, L, Jiang, H, Luo, C, Yang, C.-G. | Deposit date: | 2011-07-09 | Release date: | 2011-09-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural switching of Staphylococcus aureus Clp protease: a key to understanding protease dynamics J.Biol.Chem., 286, 2011
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3ST9
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![BU of 3st9 by Molmil](/molmil-images/mine/3st9) | Crystal structure of ClpP in heptameric form from Staphylococcus aureus | Descriptor: | ATP-dependent Clp protease proteolytic subunit, CALCIUM ION, GLYCEROL, ... | Authors: | Zhang, J, Ye, F, Lan, L, Jiang, H, Luo, C, Yang, C.-G. | Deposit date: | 2011-07-09 | Release date: | 2011-09-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural switching of Staphylococcus aureus Clp protease: a key to understanding protease dynamics J.Biol.Chem., 286, 2011
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7UW6
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![BU of 7uw6 by Molmil](/molmil-images/mine/7uw6) | The co-crystal structure of low molecular weight protein tyrosine phosphatase (LMW-PTP) with a small molecule inhibitor SPAA-2 | Descriptor: | 2-[(1,3-benzothiazol-2-yl)amino]-2-oxoethane-1-sulfonic acid, Low molecular weight phosphotyrosine protein phosphatase | Authors: | Wang, J, Zhang, Z.Y. | Deposit date: | 2022-05-02 | Release date: | 2022-10-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J.Med.Chem., 65, 2022
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6VSJ
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![BU of 6vsj by Molmil](/molmil-images/mine/6vsj) | Cryo-electron microscopy structure of mouse coronavirus spike protein complexed with its murine receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 1, Spike glycoprotein | Authors: | Shang, J, Wan, Y.S, Liu, C, Yount, B, Gully, K, Yang, Y, Auerbach, A, Peng, G.Q, Baric, R, Li, F. | Deposit date: | 2020-02-11 | Release date: | 2020-03-04 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry. Plos Pathog., 16, 2020
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4L23
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![BU of 4l23 by Molmil](/molmil-images/mine/4l23) | Crystal Structure of p110alpha complexed with niSH2 of p85alpha and PI-103 | Descriptor: | 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | Authors: | Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. | Deposit date: | 2013-06-04 | Release date: | 2014-01-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
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