5Z9Y
Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP
Summary for 5Z9Y
Entry DOI | 10.2210/pdb5z9y/pdb |
Descriptor | Thiazole synthase, 1-DEOXY-D-XYLULOSE-5-PHOSPHATE (3 entities in total) |
Functional Keywords | alpha-beta barrel, covalently bound, carbinolamine intermediate, biosynthetic protein, transferase |
Biological source | Mycobacterium tuberculosis H37Rv |
Cellular location | Cytoplasm : P9WG73 |
Total number of polymer chains | 2 |
Total formula weight | 52161.53 |
Authors | |
Primary citation | Zhang, J.,Zhang, B.,Zhao, Y.,Yang, X.,Huang, M.,Cui, P.,Zhang, W.,Li, J.,Zhang, Y. Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG). Biochem. Biophys. Res. Commun., 497:214-219, 2018 Cited by PubMed: 29428731DOI: 10.1016/j.bbrc.2018.02.056 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
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