7N0H

CryoEM structure of SARS-CoV-2 spike protein (S-6P, 2-up) in complex with sybodies (Sb45)

Summary for 7N0H

• Entry DOI: 10.2210/pdb7n0h/pdb
• Related: 6XKL 7KGJ 7KGK 7KLW 7MFU 7N0G
• EMDB information: 24105 24106
• Descriptor: Spike glycoprotein, Synthetic nanobody (Sb45), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sars-cov-2, spike protein, s-6p (hexapro), nanobody, sybody, sb45, neutralization, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 5
• Total formula weight: 468281.47

Authors

Jiang, J.,Huang, R.,Margulies, D. (deposition date: 2021-05-25, release date: 2021-06-02, Last modification date: 2021-10-20)

• Primary citation: Ahmad, J.,Jiang, J.,Boyd, L.F.,Zeher, A.,Huang, R.,Xia, D.,Natarajan, K.,Margulies, D.H.; Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.; J.Biol.Chem., 297:101202-101202, 2021; PubMed: 34537245; DOI: 10.1016/j.jbc.2021.101202

Experimental method

ELECTRON MICROSCOPY (3.34 Å)