2F76
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![BU of 2f76 by Molmil](/molmil-images/mine/2f76) | Solution structure of the M-PMV wild type matrix protein (p10) | Descriptor: | Core protein p10 | Authors: | Vlach, J, Lipov, J, Veverka, V, Lang, J, Srb, P, Rumlova, M, Hunter, E, Ruml, T, Hrabal, R. | Deposit date: | 2005-11-30 | Release date: | 2006-12-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein. Proc.Natl.Acad.Sci.USA, 105, 2008
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1MIT
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![BU of 1mit by Molmil](/molmil-images/mine/1mit) | RECOMBINANT CUCURBITA MAXIMA TRYPSIN INHIBITOR V (RCMTI-V) (NMR, MINIMIZED AVERAGE STRUCTURE) | Descriptor: | TRYPSIN INHIBITOR V | Authors: | Cai, M, Gong, Y, Huang, Y, Liu, J, Prakash, O, Wen, L, Wen, J.J, Huang, J.-K, Krishnamoorthi, R. | Deposit date: | 1995-10-26 | Release date: | 1996-04-03 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of recombinant Cucurbita maxima trypsin inhibitor-V determined by NMR spectroscopy. Biochemistry, 35, 1996
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2QUR
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![BU of 2qur by Molmil](/molmil-images/mine/2qur) | Crystal Structure of F327A/K285P Mutant of cAMP-dependent Protein Kinase | Descriptor: | 20-mer fragment from cAMP-dependent protein kinase inhibitor alpha, ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase, ... | Authors: | Taylor, S.S, Yang, J, Wu, J. | Deposit date: | 2007-08-06 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Contribution of non-catalytic core residues to activity and regulation in protein kinase A. J.Biol.Chem., 284, 2009
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1NHZ
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![BU of 1nhz by Molmil](/molmil-images/mine/1nhz) | Crystal Structure of the Antagonist Form of Glucocorticoid Receptor | Descriptor: | 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, GLUCOCORTICOID RECEPTOR, HEXANE-1,6-DIOL | Authors: | Kauppi, B, Jakob, C, Farnegardh, M, Yang, J, Ahola, H, Alarcon, M, Calles, K, Engstrom, O, Harlan, J, Muchmore, S, Ramqvist, A.-K, Thorell, S, Ohman, L, Greer, J, Gustafsson, J.-A, Carlstedt-Duke, J, Carlquist, M. | Deposit date: | 2002-12-20 | Release date: | 2003-05-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain:
RU-486 INDUCES A TRANSCONFORMATION THAT LEADS TO ACTIVE ANTAGONISM. J.Biol.Chem., 278, 2003
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2QKH
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![BU of 2qkh by Molmil](/molmil-images/mine/2qkh) | Crystal structure of the extracellular domain of human GIP receptor in complex with the hormone GIP | Descriptor: | Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, D(-)-TARTARIC ACID, Glucose-dependent insulinotropic polypeptide, ... | Authors: | Parthier, C, Kleinschmidt, M, Neumann, P, Rudolph, R, Manhart, S, Schlenzig, D, Fanghanel, J, Rahfeld, J.-U, Demuth, H.-U, Stubbs, M.T. | Deposit date: | 2007-07-11 | Release date: | 2007-08-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor Proc.Natl.Acad.Sci.Usa, 104, 2007
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1IX1
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![BU of 1ix1 by Molmil](/molmil-images/mine/1ix1) | Crystal Structure of P.aeruginosa Peptide deformylase Complexed with Antibiotic Actinonin | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, ACTINONIN, ZINC ION, ... | Authors: | Kim, H.-W, Yoon, H.-J, Lee, J.Y, Han, B.W, Yang, J.K, Lee, B.I, Ahn, H.J, Lee, H.H, Suh, S.W. | Deposit date: | 2002-06-07 | Release date: | 2003-09-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent Proteins, 57, 2004
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1SJW
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![BU of 1sjw by Molmil](/molmil-images/mine/1sjw) | Structure of polyketide cyclase SnoaL | Descriptor: | METHYL 5,7-DIHYDROXY-2-METHYL-4,6,11-TRIOXO-3,4,6,11-TETRAHYDROTETRACENE-1-CARBOXYLATE, nogalonic acid methyl ester cyclase | Authors: | Sultana, A, Kallio, P, Jansson, A, Wang, J.S, Neimi, J, Mantsala, P, Schneider, G, Structural Proteomics in Europe (SPINE) | Deposit date: | 2004-03-04 | Release date: | 2004-04-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation. Embo J., 23, 2004
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2I87
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![BU of 2i87 by Molmil](/molmil-images/mine/2i87) | Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies | Descriptor: | D-alanine-D-alanine ligase, SULFATE ION | Authors: | Liu, S, Chang, J.S, Herberg, J.T, Horng, M, Tomich, P.K, Lin, A.H, Marotti, K.R. | Deposit date: | 2006-09-01 | Release date: | 2006-10-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2XQU
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![BU of 2xqu by Molmil](/molmil-images/mine/2xqu) | Microscopic rotary mechanism of ion translocation in the Fo complex of ATP synthases | Descriptor: | ATP SYNTHASE C CHAIN, CYMAL-4 | Authors: | Pogoryelov, D, Krah, A, Langer, J, Yildiz, O, Faraldo-Gomez, J.D, Meier, T. | Deposit date: | 2010-09-07 | Release date: | 2010-10-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Microscopic Rotary Mechanism of Ion Translocation in the Fo Complex of ATP Synthases Nat.Chem.Biol., 6, 2010
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1SYK
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![BU of 1syk by Molmil](/molmil-images/mine/1syk) | Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation | Descriptor: | cAMP-dependent protein kinase, alpha-catalytic subunit | Authors: | Wu, J, Yang, J, Madhusudan, N, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S. | Deposit date: | 2004-04-01 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the E230Q mutant of cAMP-dependent
protein kinase reveals an unexpected apoenzyme conformation and an
extended N-terminal A helix. Protein Sci., 14, 2005
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2F77
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![BU of 2f77 by Molmil](/molmil-images/mine/2f77) | Solution structure of the R55F mutant of M-PMV matrix protein (p10) | Descriptor: | Core protein p10 | Authors: | Vlach, J, Lipov, J, Veverka, V, Lang, J, Srb, P, Rumlova, M, Hunter, E, Ruml, T, Hrabal, R. | Deposit date: | 2005-11-30 | Release date: | 2006-12-05 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein. Proc.Natl.Acad.Sci.USA, 105, 2008
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1ECL
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![BU of 1ecl by Molmil](/molmil-images/mine/1ecl) | |
1TAU
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![BU of 1tau by Molmil](/molmil-images/mine/1tau) | TAQ POLYMERASE (E.C.2.7.7.7)/DNA/B-OCTYLGLUCOSIDE COMPLEX | Descriptor: | 2-O-octyl-beta-D-glucopyranose, DNA (5'-D(*CP*GP*GP*AP*TP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*AP*TP*CP*CP*G)-3'), ... | Authors: | Eom, S.H, Wang, J, Steitz, T.A. | Deposit date: | 1996-06-17 | Release date: | 1997-04-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Taq ploymerase with DNA at the polymerase active site. Nature, 382, 1996
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1DT0
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![BU of 1dt0 by Molmil](/molmil-images/mine/1dt0) | CLONING, SEQUENCE, AND CRYSTALLOGRAPHIC STRUCTURE OF RECOMBINANT IRON SUPEROXIDE DISMUTASE FROM PSEUDOMONAS OVALIS | Descriptor: | FE (III) ION, SUPEROXIDE DISMUTASE | Authors: | Bond, C.J, Huang, J, Hajduk, R, Flick, K, Heath, P, Stoddard, B.L. | Deposit date: | 2000-01-10 | Release date: | 2000-12-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cloning, sequence and crystallographic structure of recombinant iron superoxide dismutase from Pseudomonas ovalis. Acta Crystallogr.,Sect.D, 56, 2000
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2HYM
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![BU of 2hym by Molmil](/molmil-images/mine/2hym) | NMR based Docking Model of the Complex between the Human Type I Interferon Receptor and Human Interferon alpha-2 | Descriptor: | Interferon alpha-2, Soluble IFN alpha/beta receptor | Authors: | Quadt-Akabayov, S.R, Chill, J.H, Levy, R, Kessler, N, Anglister, J. | Deposit date: | 2006-08-07 | Release date: | 2006-10-10 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex Protein Sci., 15, 2006
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1XDS
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![BU of 1xds by Molmil](/molmil-images/mine/1xds) | Crystal structure of Aclacinomycin-10-hydroxylase (RdmB) in complex with S-adenosyl-L-methionine (SAM) and 11-deoxy-beta-rhodomycin (DbrA) | Descriptor: | 11-DEOXY-BETA-RHODOMYCIN, Protein RdmB, S-ADENOSYLMETHIONINE | Authors: | Jansson, A, Koskiniemi, H, Erola, A, Wang, J, Mantsala, P, Schneider, G, Niemi, J, Structural Proteomics in Europe (SPINE) | Deposit date: | 2004-09-08 | Release date: | 2004-11-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Aclacinomycin 10-Hydroxylase Is a Novel Substrate-assisted Hydroxylase Requiring S-Adenosyl-L-methionine as Cofactor J.Biol.Chem., 280, 2005
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1XDU
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![BU of 1xdu by Molmil](/molmil-images/mine/1xdu) | Crystal structure of Aclacinomycin-10-hydroxylase (RdmB) in complex with Sinefungin (SFG) | Descriptor: | ACETATE ION, Protein RdmB, SINEFUNGIN | Authors: | Jansson, A, Koskiniemi, H, Erola, A, Wang, J, Mantsala, P, Schneider, G, Niemi, J. | Deposit date: | 2004-09-08 | Release date: | 2004-11-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Aclacinomycin 10-Hydroxylase Is a Novel Substrate-assisted Hydroxylase Requiring S-Adenosyl-L-methionine as Cofactor J.Biol.Chem., 280, 2005
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1XI1
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![BU of 1xi1 by Molmil](/molmil-images/mine/1xi1) | Phi29 DNA polymerase ssDNA complex, monoclinic crystal form | Descriptor: | 5'-D(P*TP*TP*TP*TP*T)-3', DNA polymerase, MAGNESIUM ION | Authors: | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | Deposit date: | 2004-09-21 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Correction of X-ray intensities from single crystals containing lattice-translocation defects Acta Crystallogr.,Sect.D, 61, 2005
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1XK9
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![BU of 1xk9 by Molmil](/molmil-images/mine/1xk9) | Pseudomanas exotoxin A in complex with the PJ34 inhibitor | Descriptor: | Exotoxin A, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE | Authors: | Yates, S.P, Taylor, P.J, Joergensen, R, Ferrraris, D, Zhang, J, Andersen, G.R, Merrill, A.R. | Deposit date: | 2004-09-28 | Release date: | 2005-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa BIOCHEM.J., 385, 2005
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2XQT
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![BU of 2xqt by Molmil](/molmil-images/mine/2xqt) | Microscopic rotary mechanism of ion translocation in the Fo complex of ATP synthases | Descriptor: | ATP SYNTHASE C CHAIN, CYMAL-4, DICYCLOHEXYLUREA | Authors: | Pogoryelov, D, Krah, A, Langer, J, Yildiz, O, Faraldo-Gomez, J.D, Meier, T. | Deposit date: | 2010-09-07 | Release date: | 2010-10-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Microscopic Rotary Mechanism of Ion Translocation in the Fo Complex of ATP Synthases Nat.Chem.Biol., 6, 2010
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1GZO
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![BU of 1gzo by Molmil](/molmil-images/mine/1gzo) | |
1GZK
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![BU of 1gzk by Molmil](/molmil-images/mine/1gzk) | |
2G94
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![BU of 2g94 by Molmil](/molmil-images/mine/2g94) | Crystal structure of beta-secretase bound to a potent and highly selective inhibitor. | Descriptor: | Beta-secretase 1, N~2~-[(2R,4S,5S)-5-{[N-{[(3,5-DIMETHYL-1H-PYRAZOL-1-YL)METHOXY]CARBONYL}-3-(METHYLSULFONYL)-L-ALANYL]AMINO}-4-HYDROXY-2,7-DIMETHYLOCTANOYL]-N-ISOBUTYL-L-VALINAMIDE | Authors: | Hong, L, Ghosh, A, Tang, J. | Deposit date: | 2006-03-05 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. J.Am.Chem.Soc., 128, 2006
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2V5Q
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![BU of 2v5q by Molmil](/molmil-images/mine/2v5q) | CRYSTAL STRUCTURE OF WILD-TYPE PLK-1 KINASE DOMAIN IN COMPLEX WITH A SELECTIVE DARPIN | Descriptor: | DESIGN ANKYRIN REPEAT PROTEIN, SERINE/THREONINE-PROTEIN KINASE PLK1 | Authors: | Bandeiras, T.M, Hillig, R.C, Matias, P.M, Eberspaecher, U, Fanghaenel, J, Thomaz, M, Miranda, S, Crusius, K, Puetter, V, Amstutz, P, Gulotti-Georgieva, M, Binz, H.K, Holz, C, Schmitz, A.A.P, Lang, C, Donner, P, Egner, U, Carrondo, M.A, Mueller-Tiemann, B. | Deposit date: | 2007-07-08 | Release date: | 2008-04-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin. Acta Crystallogr. D Biol. Crystallogr., 64, 2008
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2XQS
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![BU of 2xqs by Molmil](/molmil-images/mine/2xqs) | Microscopic rotary mechanism of ion translocation in the Fo complex of ATP synthases | Descriptor: | ATP SYNTHASE C CHAIN, CYMAL-4 | Authors: | Pogoryelov, D, Krah, A, Langer, J, Yildiz, O, Faraldo-Gomez, J.D, Meier, T. | Deposit date: | 2010-09-07 | Release date: | 2010-10-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Microscopic Rotary Mechanism of Ion Translocation in the Fo Complex of ATP Synthases Nat.Chem.Biol., 6, 2010
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