1GZK

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

Summary for 1GZK

Entry DOI	10.2210/pdb1gzk/pdb
Related	1GZN 1GZO 1O6K 1O6L
Descriptor	RAC-BETA SERINE/THREONINE PROTEIN KINASE (2 entities in total)
Functional Keywords	kinase, transferase, serine/threonine-protein kinase, atp-binding
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	36490.88
Authors	Barford, D.,Yang, J.,Hemmings, B.A. (deposition date: 2002-05-23, release date: 2003-05-22, Last modification date: 2023-12-13)
Primary citation	Yang, J.,Cron, P.,Thompson, V.,Good, V.,Hess, D.,Hemmings, B.A.,Barford, D. Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation Mol.Cell, 9:1227-, 2002 Cited by PubMed: 12086620 DOI: 10.1016/S1097-2765(02)00550-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation