2V5Q

CRYSTAL STRUCTURE OF WILD-TYPE PLK-1 KINASE DOMAIN IN COMPLEX WITH A SELECTIVE DARPIN

Summary for 2V5Q

• Entry DOI: 10.2210/pdb2v5q/pdb
• Related: 1Q4K 1Q4O 1UMW
• Descriptor: SERINE/THREONINE-PROTEIN KINASE PLK1, DESIGN ANKYRIN REPEAT PROTEIN (3 entities in total)
• Functional Keywords: design ankyrin repeat protein, transferase complex, phosphorylation, nucleotide-binding, serine/threonine-protein kinase, kinase, nucleus, transferase, atp-binding, serine/threonine protein kinase
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 107617.68

Authors

Bandeiras, T.M.,Hillig, R.C.,Matias, P.M.,Eberspaecher, U.,Fanghaenel, J.,Thomaz, M.,Miranda, S.,Crusius, K.,Puetter, V.,Amstutz, P.,Gulotti-Georgieva, M.,Binz, H.K.,Holz, C.,Schmitz, A.A.P.,Lang, C.,Donner, P.,Egner, U.,Carrondo, M.A.,Mueller-Tiemann, B. (deposition date: 2007-07-08, release date: 2008-04-01, Last modification date: 2023-12-13)

• Primary citation: Bandeiras, T.M.,Hillig, R.C.,Matias, P.M.,Eberspaecher, U.,Fanghanel, J.,Thomaz, M.,Miranda, S.,Crusius, K.,Putter, V.,Amstutz, P.,Gulotti-Georgieva, M.,Binz, H.K.,Holz, C.,Schmitz, A.A.,Lang, C.,Donner, P.,Egner, U.,Carrondo, M.A.,Muller-Tiemann, B.; Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.; Acta Crystallogr. D Biol. Crystallogr., 64:339-353, 2008; PubMed: 18391401; DOI: 10.1107/S0907444907068217

Experimental method

X-RAY DIFFRACTION (2.3 Å)