1Q4K

The polo-box domain of Plk1 in complex with a phospho-peptide

Summary for 1Q4K

• Entry DOI: 10.2210/pdb1q4k/pdb
• Descriptor: Serine/threonine-protein kinase PLK, Phospho-peptide sequence Met.Gln.Ser.pThr.Pro.Leu (3 entities in total)
• Functional Keywords: six-stranded anti-parallel beta sheet with one alpha helix, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P53350
• Total number of polymer chains: 6
• Total formula weight: 91853.43

Authors

Cheng, K.,Lowe, E.D.,Sinclair, J.,Nigg, E.A.,Johnson, L.N. (deposition date: 2003-08-04, release date: 2003-11-11, Last modification date: 2024-04-03)

• Primary citation: Cheng, K.Y.,Lowe, E.D.,Sinclair, J.,Nigg, E.A.,Johnson, L.N.; The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex.; Embo J., 22:5757-5768, 2003; PubMed: 14592974; DOI: 10.1093/emboj/cdg558

Experimental method

X-RAY DIFFRACTION (2.3 Å)