2V5Q

CRYSTAL STRUCTURE OF WILD-TYPE PLK-1 KINASE DOMAIN IN COMPLEX WITH A SELECTIVE DARPIN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	SERINE/THREONINE-PROTEIN KINASE PLK1	polymer	315	35972.9	2	UniProt (P53350) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	PLK-1, SERINE/THREONINE-PROTEIN KINASE 13, STPK13, POLO-LIKE KINASE 1, HUMAN POLO-LIKE KINASE 1
2	C, D (C, D)	DESIGN ANKYRIN REPEAT PROTEIN	polymer	167	17836.0	2		synthetic construct
3	E, F, G, H (A, B, C, D)	water	water		18.0	406	Chemie (HOH)

Sequence modifications

A, B: 31 - 32 (PDB: 2V5Q)
A, B: 33 - 345 (UniProt: P53350)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	107617.7
All*	Total formula weight	107617.7

*Water molecules are not included.