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7KN3
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BU of 7kn3 by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, S-B8 Fab heavy chain, ...
Authors:Liu, H, Zhu, X, Wilson, I.A.
Deposit date:2020-11-04
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
6CT5
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BU of 6ct5 by Molmil
PptT PAP(CoA) 8918 complex
Descriptor: 4'-phosphopantetheinyl transferase, COENZYME A, DIMETHYL SULFOXIDE, ...
Authors:Mosior, J, Sacchettini, J, TB Structural Genomics Consortium (TBSGC)
Deposit date:2018-03-22
Release date:2019-02-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.759346 Å)
Cite:Opposing reactions in coenzyme A metabolism sensitizeMycobacterium tuberculosisto enzyme inhibition.
Science, 363, 2019
4PY4
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BU of 4py4 by Molmil
Crystal structure of human poly(ADP-ribose) polymerase 14, catalytic domain in complex with an inhibitor XL2
Descriptor: 2-({4-[(1R)-1-(dimethylamino)ethyl]phenyl}amino)-6-fluoro-1,3-benzothiazole-4-carboxamide, Poly [ADP-ribose] polymerase 14
Authors:Li, J, Xu, Y.
Deposit date:2014-03-26
Release date:2015-04-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Palladium-catalyzed N-arylation of 2-aminobenzothiazole-4-carboxylates/carboxamides: facile synthesis of PARP14 inhibitors
Tetrahedron, 70, 2017
4QS4
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BU of 4qs4 by Molmil
Crystal Structure of CofB from Enterotoxigenic Escherichia coli
Descriptor: CofB, GLYCEROL, SULFATE ION
Authors:Kolappan, S, Craig, L.
Deposit date:2014-07-02
Release date:2015-06-03
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Minor Pilin CofB, the Initiator of CFA/III Pilus Assembly in Enterotoxigenic Escherichia coli.
J.Biol.Chem., 290, 2015
5WRE
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BU of 5wre by Molmil
Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01)
Descriptor: (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl)pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ...
Authors:Zhou, Z, Xu, Z.H.
Deposit date:2016-12-01
Release date:2017-02-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.946 Å)
Cite:Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
2JWE
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BU of 2jwe by Molmil
Solution structure of the second PDZ domain from human zonula occludens-1: A dimeric form with 3D domain swapping
Descriptor: Tight junction protein ZO-1
Authors:Ji, P, Wu, J.W, Zhang, J.H, Yang, Y.S, Wu, J.H, Shi, Y.Y.
Deposit date:2007-10-10
Release date:2007-10-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the second PDZ domain of Zonula Occludens 1
Proteins, 79, 2011
7XUF
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BU of 7xuf by Molmil
Cryo-EM structure of the AKT1-AtKC1 complex from Arabidopsis thaliana
Descriptor: POTASSIUM ION, Potassium channel AKT1, Potassium channel KAT3
Authors:Yang, G.H, Lu, Y.M, Jia, Y.T, Yang, F, Zhang, Y.M, Xu, X, Li, X.M, Lei, J.L.
Deposit date:2022-05-18
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
7WSW
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BU of 7wsw by Molmil
Cryo-EM structure of the Potassium channel AKT1 from Arabidopsis thaliana
Descriptor: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
Authors:Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
Deposit date:2022-02-02
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
6LFB
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BU of 6lfb by Molmil
E. coli Thioesterase I mutant DG
Descriptor: Acyl-CoA thioesterase I also functions as protease I
Authors:Deng, X, Chen, L, Yang, G.
Deposit date:2019-12-01
Release date:2020-07-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure-guided reshaping of the acyl binding pocket of 'TesA thioesterase enhances octanoic acid production in E. coli.
Metab. Eng., 61, 2020
6LFC
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BU of 6lfc by Molmil
E. coli Thioesterase I mutant DG
Descriptor: Acyl-CoA thioesterase I also functions as protease I
Authors:Deng, X, Chen, L, Yang, G.
Deposit date:2019-12-01
Release date:2020-07-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-guided reshaping of the acyl binding pocket of 'TesA thioesterase enhances octanoic acid production in E. coli.
Metab. Eng., 61, 2020
3NKS
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BU of 3nks by Molmil
Structure of human protoporphyrinogen IX oxidase
Descriptor: 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-NITROBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Shen, Y.
Deposit date:2010-06-21
Release date:2011-04-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insight into human variegate porphyria disease
Faseb J., 25, 2011
6KMH
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BU of 6kmh by Molmil
The crystal structure of CASK/Mint1 complex
Descriptor: Amyloid-beta A4 precursor protein-binding family A member 1, CHLORIDE ION, IODIDE ION, ...
Authors:Li, W, Feng, W.
Deposit date:2019-07-31
Release date:2020-08-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion.
Cell Discov, 6, 2020
6JYZ
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BU of 6jyz by Molmil
Crystal structure of endogalactoceramidase
Descriptor: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ISOPROPYL ALCOHOL, ...
Authors:Liuqing, C, Yan, F.
Deposit date:2019-04-29
Release date:2019-10-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of an endogalactosylceramidase from Rhodococcus hoagii 103S reveals the molecular basis of its substrate specificity.
J.Struct.Biol., 208, 2019
6L77
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BU of 6l77 by Molmil
Crystal structure of MS5 from Brassica napus
Descriptor: MS5a
Authors:Wang, X, Guan, Z.Y, Yin, P.
Deposit date:2019-10-31
Release date:2020-06-03
Last modified:2020-12-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the meiosis-related protein MS5 reveals non-canonical papain enhancement by cystatin-like folds.
Febs Lett., 594, 2020
6NTE
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BU of 6nte by Molmil
Crystal Structure of Synechocystis Dihydroxyacid Dehydratase (DHAD)
Descriptor: Dihydroxy-acid dehydratase
Authors:MacTavish, B, Bruner, S.
Deposit date:2019-01-29
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Cyanobacterial Dihydroxyacid Dehydratases Are a Promising Growth Inhibition Target.
Acs Chem.Biol., 15, 2020
7FCV
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BU of 7fcv by Molmil
Cryo-EM structure of the Potassium channel AKT1 mutant from Arabidopsis thaliana
Descriptor: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
Authors:Yang, G.H, Lu, Y.M, Jia, Y.T, Zhang, Y.M, Tang, R.F, Xu, X, Li, X.M, Lei, J.L.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
6O6T
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BU of 6o6t by Molmil
Crystal structure of Csm6 H132A mutant
Descriptor: Csm6
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O71
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BU of 6o71 by Molmil
Crystal structure of Csm6 in complex with cdA4 by soaking cdA4 into Csm6
Descriptor: Csm6, Cyclic DNA cdA4
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
3UIV
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BU of 3uiv by Molmil
Human serum albumin-myristate-amantadine hydrochloride complex
Descriptor: (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, MYRISTIC ACID, Serum albumin
Authors:Yang, F, Ma, Z, Ma, L, Yang, G.
Deposit date:2011-11-06
Release date:2012-11-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of the drug-binding specificity of human serum albumin
TO BE PUBLISHED
7VR1
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BU of 7vr1 by Molmil
Cryo-EM structure of the ATP-binding cassette sub-family D member 1 from Homo sapiens
Descriptor: ATP-binding cassette sub-family D member 1
Authors:Yang, G.H, Jia, Y.T, Zhang, Y.M.
Deposit date:2021-10-21
Release date:2022-10-26
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural and functional insights of the human peroxisomal ABC transporter ALDP.
Elife, 11, 2022
8GKF
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BU of 8gkf by Molmil
Phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis in complex with Raltitrexed.
Descriptor: 4'-phosphopantetheinyl transferase PptT, TOMUDEX
Authors:Krieger, I.V, Singh, A, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2023-03-18
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.
Sci Adv, 10, 2024
8HCQ
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BU of 8hcq by Molmil
Cryo-EM structure of endothelin1-bound ETAR-Gq complex
Descriptor: Endothelin-1, Endothelin-1 receptor,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J.
Deposit date:2022-11-02
Release date:2023-03-22
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
8HCX
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BU of 8hcx by Molmil
Cryo-EM structure of Endothelin1-bound ETBR-Gq complex
Descriptor: Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J.
Deposit date:2022-11-03
Release date:2023-03-22
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
8HBD
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BU of 8hbd by Molmil
Cryo-EM structure of IRL1620-bound ETBR-Gi complex
Descriptor: Endothelin receptor type B,Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Yuan, Q, Ji, Y, Jiang, Y, Duan, J, Xu, H.E.
Deposit date:2022-10-28
Release date:2023-03-22
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
4LA2
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BU of 4la2 by Molmil
Crystal structure of dimethylsulphoniopropionate (DMSP) lyase DddQ
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Dimethylsulphoniopropionate (DMSP) lyase DddQ, ZINC ION
Authors:Zhang, Y, Li, C.
Deposit date:2013-06-19
Release date:2014-01-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular insight into bacterial cleavage of oceanic dimethylsulfoniopropionate into dimethyl sulfide
Proc.Natl.Acad.Sci.USA, 111, 2014

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数据于2024-05-22公开中

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