6O6T

Crystal structure of Csm6 H132A mutant

Summary for 6O6T

Entry DOI	10.2210/pdb6o6t/pdb
Descriptor	Csm6 (2 entities in total)
Functional Keywords	type iii-a crispr-cas system; csm6, immune system
Biological source	Thermococcus onnurineus (strain NA1)
Total number of polymer chains	2
Total formula weight	99456.09
Authors	Jia, N.,Patel, D.J. (deposition date: 2019-03-07, release date: 2019-07-31, Last modification date: 2023-10-11)
Primary citation	Jia, N.,Jones, R.,Yang, G.,Ouerfelli, O.,Patel, D.J. CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75:944-956.e6, 2019 Cited by PubMed: 31326273 DOI: 10.1016/j.molcel.2019.06.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation