6CT5

PptT PAP(CoA) 8918 complex

Summary for 6CT5

• Entry DOI: 10.2210/pdb6ct5/pdb
• Descriptor: 4'-phosphopantetheinyl transferase, COENZYME A, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, ... (7 entities in total)
• Functional Keywords: inhibitor, complex, structural genomics, tb structural genomics consortium, tbsgc, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 56976.57

Authors

Mosior, J.,Sacchettini, J.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2018-03-22, release date: 2019-02-06, Last modification date: 2023-10-04)

• Primary citation: Ballinger, E.,Mosior, J.,Hartman, T.,Burns-Huang, K.,Gold, B.,Morris, R.,Goullieux, L.,Blanc, I.,Vaubourgeix, J.,Lagrange, S.,Fraisse, L.,Sans, S.,Couturier, C.,Bacque, E.,Rhee, K.,Scarry, S.M.,Aube, J.,Yang, G.,Ouerfelli, O.,Schnappinger, D.,Ioerger, T.R.,Engelhart, C.A.,McConnell, J.A.,McAulay, K.,Fay, A.,Roubert, C.,Sacchettini, J.,Nathan, C.; Opposing reactions in coenzyme A metabolism sensitizeMycobacterium tuberculosisto enzyme inhibition.; Science, 363:-, 2019; PubMed: 30705156; DOI: 10.1126/science.aau8959

Experimental method

X-RAY DIFFRACTION (1.75934602056 Å)