3NKS

Structure of human protoporphyrinogen IX oxidase

Summary for 3NKS

• Entry DOI: 10.2210/pdb3nks/pdb
• Related: 3I6D
• Descriptor: Protoporphyrinogen oxidase, 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-NITROBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: fad containing protein, ppo, variegate porphyria disease, vp, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side (By similarity): P50336
• Total number of polymer chains: 1
• Total formula weight: 52152.51

Authors

Shen, Y. (deposition date: 2010-06-21, release date: 2011-04-20, Last modification date: 2023-11-01)

• Primary citation: Qin, X.,Tan, Y.,Wang, L.,Wang, Z.,Wang, B.,Wen, X.,Yang, G.,Xi, Z.,Shen, Y.; Structural insight into human variegate porphyria disease; Faseb J., 25:653-664, 2011; PubMed: 21048046; DOI: 10.1096/fj.10-170811

Experimental method

X-RAY DIFFRACTION (1.9 Å)