6O71

Crystal structure of Csm6 in complex with cdA4 by soaking cdA4 into Csm6

Summary for 6O71

Entry DOI	10.2210/pdb6o71/pdb
Descriptor	Csm6, Cyclic DNA cdA4 (2 entities in total)
Functional Keywords	type iii-a crispr-cas system; csm6 in complex with cda4, immune system, immune system-dna complex, immune system/dna
Biological source	Thermococcus onnurineus More
Total number of polymer chains	4
Total formula weight	102005.97
Authors	Jia, N.,Patel, D.J. (deposition date: 2019-03-07, release date: 2019-07-31, Last modification date: 2024-03-13)
Primary citation	Jia, N.,Jones, R.,Yang, G.,Ouerfelli, O.,Patel, D.J. CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75:944-956.e6, 2019 Cited by PubMed: 31326273 DOI: 10.1016/j.molcel.2019.06.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation