8TNH
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8TNI
| Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP gp120, ... | 著者 | Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D, Xu, J. | 登録日 | 2023-08-01 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex To Be Published
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8TNG
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5DDW
| Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with the PMP external aldimine adduct with Caerulomycin M | 分子名称: | CrmG, GLYCEROL, [5-hydroxy-4-({(E)-[(4-hydroxy-2,2'-bipyridin-6-yl)methylidene]amino}methyl)-6-methylpyridin-3-yl]methyl dihydrogen phosphate | 著者 | Xu, J, Feng, Z, Liu, J. | 登録日 | 2015-08-25 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis Acs Chem.Biol., 11, 2016
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5DDS
| Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with PLP | 分子名称: | ACETIC ACID, CrmG, GLYCEROL, ... | 著者 | Xu, J, Feng, Z, Liu, J. | 登録日 | 2015-08-25 | 公開日 | 2016-08-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis Acs Chem.Biol., 11, 2016
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5XE1
| Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with INCB14943 | 分子名称: | 4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboxamidine, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Xu, J, Wu, U, Liu, J. | 登録日 | 2017-03-31 | 公開日 | 2017-05-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the binding mechanism of IDO1 with hydroxylamidine based inhibitor INCB14943 Biochem. Biophys. Res. Commun., 487, 2017
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3W94
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4NPK
| Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound | 分子名称: | CALCIUM ION, Extended synaptotagmin-2 | 著者 | Tomchick, D.R, Rizo, J, Xu, J. | 登録日 | 2013-11-21 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.552 Å) | 主引用文献 | Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2. Structure, 22, 2014
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4NPJ
| Extended-Synaptotagmin 2, C2A- and C2B-domains | 分子名称: | ACETATE ION, CHLORIDE ION, Extended synaptotagmin-2, ... | 著者 | Tomchick, D.R, Rizo, J, Xu, J. | 登録日 | 2013-11-21 | 公開日 | 2014-01-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2. Structure, 22, 2014
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6B3Y
| Crystal structure of the PH-like domain from DENND3 | 分子名称: | DENN domain-containing protein 3 | 著者 | Kozlov, G, Xu, J, Menade, M, Beaugrand, M, Pan, T, McPherson, P.S, Gehring, K. | 登録日 | 2017-09-25 | 公開日 | 2018-01-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | 主引用文献 | A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy. J. Biol. Chem., 293, 2018
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7Y6D
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4KPR
| Tetrameric form of rat selenoprotein thioredoxin reductase 1 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, SULFITE ION, ... | 著者 | Lindqvist, Y, Sandalova, T, Xu, J, Arner, E. | 登録日 | 2013-05-14 | 公開日 | 2014-05-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Trp114 residue of thioredoxin reductase 1 is an electron relay sensor for oxidative stress To be Published, 2013
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7WKX
| IL-17A in complex with the humanized antibody HB0017 | 分子名称: | ACETIC ACID, Heavy chain of HB0017 Fab, Interleukin-17A, ... | 著者 | Xu, J, Zhu, X, He, Y. | 登録日 | 2022-01-12 | 公開日 | 2022-03-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural and functional insights into a novel pre-clinical-stage antibody targeting IL-17A for treatment of autoimmune diseases. Int.J.Biol.Macromol., 202, 2022
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7WF6
| Crystal structure of SNX13 RGS domain | 分子名称: | CHLORIDE ION, Sorting nexin-13 | 著者 | Xu, J, Zhu, J, Liu, J. | 登録日 | 2021-12-26 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins. J.Mol.Biol., 434, 2022
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8HRU
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8HRI
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8HRM
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8HRK
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8HRN
| Cryo-EM structure of ACE2 | 分子名称: | Angiotensin-converting enzyme 2 | 著者 | Xu, J, Liu, N, Wang, H.W. | 登録日 | 2022-12-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure To Be Published
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8HRL
| SARS-CoV-2 Delta S-RBD-ACE2 | 分子名称: | Processed angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Xu, J, Meng, F, Liu, N, Wang, H.W. | 登録日 | 2022-12-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure To Be Published
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8HRJ
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7W6P
| Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist | 分子名称: | Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, J, Fink, E.A, Shoichet, B.K, Du, Y. | 登録日 | 2021-12-02 | 公開日 | 2022-09-28 | 最終更新日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structure-based discovery of nonopioid analgesics acting through the alpha 2A -adrenergic receptor. Science, 377, 2022
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7W7E
| Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist | 分子名称: | 5-(3-bicyclo[4.2.0]octa-1,3,5-trienyl)-1,2,3,6-tetrahydropyridine, Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Xu, J, Fink, E.A, Shoichet, B.K, Du, Y. | 登録日 | 2021-12-04 | 公開日 | 2022-09-28 | 最終更新日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure-based discovery of nonopioid analgesics acting through the alpha 2A -adrenergic receptor. Science, 377, 2022
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7WZ4
| Structure of an orphan GPCR-G protein signaling complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Xu, J, Chen, G, Liu, Z, Du, Y. | 登録日 | 2022-02-17 | 公開日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex. Nat Commun, 13, 2022
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7EJX
| Structure of the GPR88-Gi1 signaling complex bound to a synthetic ligand | 分子名称: | (1R,2R)-N-[(2S,3S)-2-azanyl-3-methyl-pentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-yl-cyclopropane-1-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Xu, J, Chen, G, Liu, Z, Du, Y. | 登録日 | 2021-04-02 | 公開日 | 2022-04-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex. Nat Commun, 13, 2022
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