6B3Y
Crystal structure of the PH-like domain from DENND3
Summary for 6B3Y
| Entry DOI | 10.2210/pdb6b3y/pdb |
| Descriptor | DENN domain-containing protein 3 (2 entities in total) |
| Functional Keywords | autophagy, guanine nucleotide exchange factor, ph-like fold, transport protein |
| Biological source | Mus musculus (Mouse) |
| Total number of polymer chains | 2 |
| Total formula weight | 58483.83 |
| Authors | Kozlov, G.,Xu, J.,Menade, M.,Beaugrand, M.,Pan, T.,McPherson, P.S.,Gehring, K. (deposition date: 2017-09-25, release date: 2018-01-24, Last modification date: 2024-03-13) |
| Primary citation | Xu, J.,Kozlov, G.,McPherson, P.S.,Gehring, K. A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy. J. Biol. Chem., 293:4566-4574, 2018 Cited by PubMed: 29352104DOI: 10.1074/jbc.RA117.001446 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.852 Å) |
Structure validation
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