4NPJ

Extended-Synaptotagmin 2, C2A- and C2B-domains

Summary for 4NPJ

• Entry DOI: 10.2210/pdb4npj/pdb
• Related: 4NPK
• Descriptor: Extended synaptotagmin-2, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: calcium/phospholipid binding protein, c2 domain, membrane traffic, protein targeting, plasma membrane, membrane protein, er to plasma membrane
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Peripheral membrane protein: A0FGR8
• Total number of polymer chains: 2
• Total formula weight: 68721.58

Authors

Tomchick, D.R.,Rizo, J.,Xu, J. (deposition date: 2013-11-21, release date: 2014-01-29, Last modification date: 2024-02-28)

• Primary citation: Xu, J.,Bacaj, T.,Zhou, A.,Tomchick, D.R.,Sudhof, T.C.,Rizo, J.; Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2.; Structure, 22:269-280, 2014; PubMed: 24373768; DOI: 10.1016/j.str.2013.11.011

Experimental method

X-RAY DIFFRACTION (2.101 Å)