8TNG

Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site

Summary for 8TNG

• Entry DOI: 10.2210/pdb8tng/pdb
• EMDB information: 41415 41416 41417
• Descriptor: HIV-1 BG505 DS-SOSIP gp120, Envelope glycoproteiHIV-1 BG505 DS-SOSIP gp41n gp41, CD4-binding site targeting nanobody R27, ... (7 entities in total)
• Functional Keywords: hiv-1 envelope, antibody, nanobody, vhh, llama, bg505 ds-sosip, neutralization, immunization, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 9
• Total formula weight: 268771.70

Authors

Zhou, T.,Kwong, P.D.,Xu, J. (deposition date: 2023-08-01, release date: 2024-05-08)

• Primary citation: Xu, J.,Zhou, T.; Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.58 Å)