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2B7M
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BU of 2b7m by Molmil
Crystal Structure of the S. cerevisiae Exocyst Component Exo70p
Descriptor: Exocyst complex component EXO70
Authors:Hamburger, Z.A, Hamburger, A.E, West, A.P, Weis, W.I.
Deposit date:2005-10-04
Release date:2005-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal Structure of the S.cerevisiae Exocyst Component Exo70p
J.Mol.Biol., 356, 2006
2GW5
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BU of 2gw5 by Molmil
Crystal Structure of LIR-2 (ILT4) at 1.8 : differences from LIR-1 (ILT2) in regions implicated in the binding of the Cytomegalovirus class I MHC homolog UL18
Descriptor: ISOPROPYL ALCOHOL, Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor
Authors:Willcox, B.E, Thomas, L.M, Chapman, T.L, Heikema, A.P, West, A.P, Bjorkman, P.J.
Deposit date:2006-05-03
Release date:2006-06-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18.
Bmc Struct.Biol., 2, 2002
4NHG
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BU of 4nhg by Molmil
Crystal Structure of 2G12 IgG Dimer
Descriptor: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein
Authors:Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J.
Deposit date:2013-11-05
Release date:2014-02-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (8.001 Å)
Cite:Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
5T3Z
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BU of 5t3z by Molmil
3.5 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074
Descriptor: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gristick, H.B, Bjorkman, P.J.
Deposit date:2016-08-26
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site.
Nat.Struct.Mol.Biol., 23, 2016
5FEC
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BU of 5fec by Molmil
Crystal structure of 3BNC60 Fab germline precursor in complex with 426c.TM4deltaV1-3 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM4deltaV1-3 gp120, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2015-12-16
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5FA2
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BU of 5fa2 by Molmil
Crystal structure of 426c.TM4deltaV1-3 p120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, THIOCYANATE ION, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2015-12-10
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5VIC
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BU of 5vic by Molmil
Crystal structure of anti-Zika antibody Z004 bound to DENV-1 Envelope protein DIII
Descriptor: Dengue 1 Envelope DIII domain, Fab heavy chain, Fab light chain
Authors:Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J.
Deposit date:2017-04-14
Release date:2017-05-03
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Cell, 169, 2017
3P4L
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BU of 3p4l by Molmil
Crystal structure of a hemojuvelin-binding fragment of neogenin
Descriptor: Neogenin
Authors:Yang, F, West Jr, A.P, Bjorkman, P.J.
Deposit date:2010-10-06
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8A.
J.Struct.Biol., 174, 2011
4RX4
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BU of 4rx4 by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC134 Heavy chain, ...
Authors:Zhou, T, Acharya, P, Moquin, S, Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Last modified:2021-06-02
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4RWY
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BU of 4rwy by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Acharya, P, Luongo, T.S, Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.128 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
1Z6O
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BU of 1z6o by Molmil
Crystal Structure of Trichoplusia ni secreted ferritin
Descriptor: CALCIUM ION, FE (III) ION, Ferritin heavy chain, ...
Authors:Hamburger, A.E, West Jr, A.P, Hamburger, Z.A, Hamburger, P, Bjorkman, P.J.
Deposit date:2005-03-22
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains.
J.Mol.Biol., 349, 2005
3IT8
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BU of 3it8 by Molmil
Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2L protein, Tumor necrosis factor
Authors:Yang, Z, West Jr, A.P, Bjorkman, P.J.
Deposit date:2009-08-27
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of TNFalpha complexed with a poxvirus MHC-related TNF binding protein
Nat.Struct.Mol.Biol., 16, 2009
8EB2
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BU of 8eb2 by Molmil
Structure of HLA-A*02:01 in complex with NY-ESO-1 peptide and PA2.1 Fab
Descriptor: Beta-2-microglobulin, HLA-A*02:01 alpha chain, NY-ESO-1 peptide, ...
Authors:Jette, C.A, West, A.P.
Deposit date:2022-08-30
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.
Mol Ther Oncolytics, 27, 2022
5VIG
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BU of 5vig by Molmil
Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII
Descriptor: CITRATE ANION, Fab heavy chain, Fab light chain, ...
Authors:Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J.
Deposit date:2017-04-16
Release date:2017-05-03
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Cell, 169, 2017
6XJD
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BU of 6xjd by Molmil
Two mouse cGAS catalytic domain binding to human assembled nucleosome
Descriptor: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ...
Authors:Xu, P, Li, P, Zhao, B.
Deposit date:2020-06-23
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
4NHH
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BU of 4nhh by Molmil
Structure of 2G12 IgG Dimer
Descriptor: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein
Authors:Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J.
Deposit date:2013-11-05
Release date:2014-02-26
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
3U7W
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BU of 3u7w by Molmil
Crystal structure of NIH45-46 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Heavy chain, ...
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2011-10-14
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design.
Science, 334, 2011
3U7Y
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BU of 3u7y by Molmil
Structure of NIH45-46 Fab in complex with gp120 of 93TH057 HIV
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CITRATE ANION, ...
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2011-10-14
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4478 Å)
Cite:Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design.
Science, 334, 2011
5CAY
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BU of 5cay by Molmil
Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120 core from ST strain of HIV-2, ...
Authors:Davenport, Y.W, Bjorkman, P.J.
Deposit date:2015-06-30
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of an HIV-2 gp120 in Complex with CD4.
J.Virol., 90, 2015
5F7E
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BU of 5f7e by Molmil
Crystal structure of germ-line precursor of 3BNC60 Fab
Descriptor: Fab heavy chain, Fab light chain
Authors:Sievers, S.A, Scharf, L, Jiang, S, Bjorkman, P.J.
Deposit date:2015-12-08
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5IGX
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BU of 5igx by Molmil
Crystal structure of NIH45-46 Fab germline precursor in complex with 426c.TM1deltaV1-3 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM1deltaV1-3 gp120, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2016-02-28
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5I9Q
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BU of 5i9q by Molmil
Crystal structure of 3BNC55 Fab in complex with 426c.TM4deltaV1-3 gp120
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC55 Fab heavy chain, ...
Authors:Scharf, L, Chen, C, Bjorkman, P.J.
Deposit date:2016-02-20
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
2PZX
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BU of 2pzx by Molmil
Structure of the methuselah ectodomain with peptide inhibitor
Descriptor: G-protein coupled receptor Mth
Authors:West Jr, A.P, Ja, W.W, Delker, S.L, Bjorkman, P.J, Benzer, S, Roberts, R.W.
Deposit date:2007-05-18
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor.
Nat.Chem.Biol., 3, 2007
4JDT
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BU of 4jdt by Molmil
Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
Authors:Scharf, L, Diskin, R, Bjorkman, P.J.
Deposit date:2013-02-25
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JKP
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BU of 4jkp by Molmil
Restricting HIV-1 Pathways for Escape using Rationally-Designed Anti-HIV-1 Antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody 45-46M2, Light chain of antibody 45-46M2, ...
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2013-03-11
Release date:2013-05-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies.
J.Exp.Med., 210, 2013

 

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