3U7W

Crystal structure of NIH45-46 Fab

Summary for 3U7W

• Entry DOI: 10.2210/pdb3u7w/pdb
• Related: 3U7Y
• Descriptor: Heavy chain, Ig gamma-1 chain C region, Light chain, Ig kappa chain C region, GLYCEROL, ... (6 entities in total)
• Functional Keywords: ig fold, antibody, hiv gp120, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 48683.33

Authors

Diskin, R.,Bjorkman, P.J. (deposition date: 2011-10-14, release date: 2011-11-16, Last modification date: 2023-09-13)

• Primary citation: Diskin, R.,Scheid, J.F.,Marcovecchio, P.M.,West, A.P.,Klein, F.,Gao, H.,Gnanapragasam, P.N.,Abadir, A.,Seaman, M.S.,Nussenzweig, M.C.,Bjorkman, P.J.; Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design.; Science, 334:1289-1293, 2011; PubMed: 22033520; DOI: 10.1126/science.1213782

Experimental method

X-RAY DIFFRACTION (2.6 Å)