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4NHH

Structure of 2G12 IgG Dimer

Summary for 4NHH
Entry DOI10.2210/pdb4nhh/pdb
Descriptor2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein, 2G12 IgG dimer heavy chain (3 entities in total)
Functional Keywordsig, antibody, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains18
Total formula weight428576.66
Authors
Wu, Y.,West Jr., A.P.,Kim, H.J.,Thornton, M.E.,Ward, A.B.,Bjorkman, P.J. (deposition date: 2013-11-05, release date: 2014-02-26)
Primary citationWu, Y.,West, A.P.,Kim, H.J.,Thornton, M.E.,Ward, A.B.,Bjorkman, P.J.
Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5:1443-1455, 2013
Cited by
PubMed: 24316082
DOI: 10.1016/j.celrep.2013.11.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (6.5 Å)
Structure validation

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