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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

4NHH

Structure of 2G12 IgG Dimer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1L, K, G, F, Q...2G12 IgG dimer light chainpolymer21323233.96Homo sapiens (human)
2H, M, E, I, O...Hepatitis B virus receptor binding proteinpolymer22924248.46UniProt (Q6PYX1)
Pfam (PF07654)
In PDB		Homo sapiens (human)
3A, B, C, D, J...2G12 IgG dimer heavy chainpolymer21123947.16Pfam (PF07654)
UniProt (by SIFTS) (Q6PYX1)
In PDB		Homo sapiens (human)
Sequence modifications
H, M, E, I, O, R: 1 - 229 (UniProt: Q6PYX1)
PDBExternal DatabaseDetails
Glu 1Ser 140CONFLICT
Gln 3Phe 142CONFLICT
Val 5-EXPRESSION TAG
Glu 6-EXPRESSION TAG
Ser 7-EXPRESSION TAG
Gly 8-EXPRESSION TAG
Gly 9-EXPRESSION TAG
Gly 10Phe 144CONFLICT
Leu 11Pro 145CONFLICT
Val 12Pro 146CONFLICT
Ala 14Pro 148CONFLICT
Gly 15Lys 149CONFLICT
Gly 16Asp 150CONFLICT
Ser 17Thr 151CONFLICT
Ile 19Met 153CONFLICT
Leu 20Ile 154CONFLICT
-Arg 156DELETION
-Thr 157DELETION
-Pro 158DELETION
-Glu 159DELETION
-Val 160DELETION
-Thr 161DELETION
Gly 23Val 163CONFLICT
Ser 25-EXPRESSION TAG
Asn 26-EXPRESSION TAG
Phe 27Val 165CONFLICT
Arg 28Asp 166CONFLICT
Ile 29Val 167CONFLICT
Ala 31-EXPRESSION TAG
-Glu 170DELETION
-Asp 171DELETION
-Pro 172DELETION
-Glu 173DELETION
-Val 174DELETION
Thr 33Lys 175CONFLICT
Met 34Phe 176CONFLICT
Val 37-EXPRESSION TAG
Arg 38-EXPRESSION TAG
Arg 39Tyr 179CONFLICT
Pro 41-EXPRESSION TAG
Gly 42-EXPRESSION TAG
Gly 43Asp 181CONFLICT
Leu 45Val 183CONFLICT
Trp 47-EXPRESSION TAG
-His 186DELETION
-Asn 187DELETION
-Lys 189DELETION
-Thr 190DELETION
-Lys 191DELETION
-Pro 192DELETION
-Arg 193DELETION
-Glu 194DELETION
Ser 50Glu 195CONFLICT
Ile 51Gln 196CONFLICT
Ser 52Tyr 197CONFLICT
Ser 53Asn 198CONFLICT
Asp 58-EXPRESSION TAG
Tyr 59-EXPRESSION TAG
Ala 60-EXPRESSION TAG
Asp 61-EXPRESSION TAG
Ala 62-EXPRESSION TAG
Lys 64Val 204CONFLICT
Gly 65Ser 205CONFLICT
Arg 66Val 206CONFLICT
Phe 67Leu 207CONFLICT
Ser 70-EXPRESSION TAG
Arg 71-EXPRESSION TAG
Asp 72-EXPRESSION TAG
Asp 73-EXPRESSION TAG
-His 211DELETION
Glu 75Gln 212CONFLICT
Phe 77-EXPRESSION TAG
Val 78-EXPRESSION TAG
Tyr 79Trp 214CONFLICT
Gln 81-EXPRESSION TAG
Met 82Asn 216CONFLICT
His 83Gly 217CONFLICT
Arg 85-EXPRESSION TAG
Val 86-EXPRESSION TAG
Asp 88-EXPRESSION TAG
Thr 89-EXPRESSION TAG
Ala 90-EXPRESSION TAG
Ile 91-EXPRESSION TAG
Tyr 93Lys 221CONFLICT
Ala 95-EXPRESSION TAG
Arg 96-EXPRESSION TAG
Gly 98Val 224CONFLICT
-Asn 226DELETION
Asp 100Lys 227CONFLICT
Arg 101Ala 228CONFLICT
Asp 103Pro 230CONFLICT
Trp 105-EXPRESSION TAG
Gly 106-EXPRESSION TAG
Gly 108-EXPRESSION TAG
Thr 109Ile 233CONFLICT
Val 110Glu 234CONFLICT
Val 111Lys 235CONFLICT
Val 113Ile 237CONFLICT
Pro 115Lys 239CONFLICT
Ser 117-EXPRESSION TAG
Thr 118-EXPRESSION TAG
-Gln 243DELETION
-Pro 244DELETION
-Arg 245DELETION
-Glu 246DELETION
Ser 122Gln 248CONFLICT
Phe 124Tyr 250CONFLICT
Pro 125Thr 251CONFLICT
Ala 127Pro 253CONFLICT
-Arg 256DELETION
-Glu 257DELETION
-Glu 258DELETION
Gly 130Met 259CONFLICT
-Lys 261DELETION
-Asn 262DELETION
-Gln 263DELETION
Ala 132Val 264CONFLICT
Ala 133Ser 265CONFLICT
Gly 135Thr 267CONFLICT
Asp 140Gly 272CONFLICT
Tyr 141Phe 273CONFLICT
Phe 142Tyr 274CONFLICT
Glu 144Ser 276CONFLICT
Pro 145Asp 277CONFLICT
Val 146Ile 278CONFLICT
Thr 147Ala 279CONFLICT
Ser 149Glu 281CONFLICT
Asn 151Glu 283CONFLICT
-Asn 285DELETION
Ala 154Gln 287CONFLICT
Leu 155Pro 288CONFLICT
Thr 156Glu 289CONFLICT
Ser 157Asn 290CONFLICT
Gly 158Asn 291CONFLICT
Val 159Tyr 292CONFLICT
His 160Lys 293CONFLICT
Phe 162Thr 295CONFLICT
Ala 164Pro 297CONFLICT
Gln 167Asp 300CONFLICT
Ser 169Asp 302CONFLICT
-Ser 304DELETION
-Phe 305DELETION
-Phe 306DELETION
-Lys 310DELETION
Ser 175-EXPRESSION TAG
Ser 176-EXPRESSION TAG
Val 177-EXPRESSION TAG
Val 178-EXPRESSION TAG
Pro 181Asp 314CONFLICT
Ser 182Lys 315CONFLICT
-Arg 317DELETION
-Trp 318DELETION
Ser 184Gln 319CONFLICT
Leu 185Gln 320CONFLICT
Thr 187-EXPRESSION TAG
Gln 188Asn 322CONFLICT
Thr 189Val 323CONFLICT
Tyr 190Phe 324CONFLICT
Ile 191Ser 325CONFLICT
Asn 193Ser 327CONFLICT
-Met 329DELETION
-His 330DELETION
-Glu 331DELETION
-Ala 332DELETION
-Leu 333DELETION
-His 334DELETION
Lys 197-EXPRESSION TAG
Pro 198-EXPRESSION TAG
Ser 199-EXPRESSION TAG
Asn 200Tyr 337CONFLICT
Lys 202-EXPRESSION TAG
Val 203-EXPRESSION TAG
Asp 204-EXPRESSION TAG
Lys 205-EXPRESSION TAG
Lys 206-EXPRESSION TAG
Val 207-EXPRESSION TAG
Glu 208-EXPRESSION TAG
Pro 209Gln 339CONFLICT
Cys 212-EXPRESSION TAG
Asp 213-EXPRESSION TAG
Lys 214-EXPRESSION TAG
Thr 215Leu 342CONFLICT
Thr 217Leu 344CONFLICT
Cys 218Ser 345CONFLICT
Pro 220-EXPRESSION TAG
Cys 221-EXPRESSION TAG
Pro 222-EXPRESSION TAG
Ala 223-EXPRESSION TAG
Pro 224-EXPRESSION TAG
Glu 225-EXPRESSION TAG
Leu 226-EXPRESSION TAG
Leu 227-EXPRESSION TAG
Gly 229Lys 348CONFLICT
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains18
Total formula weight428576.7
All*Total formula weight428576.7
*Water molecules are not included.

218853

PDB entries from 2024-04-24

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