4JKP

Restricting HIV-1 Pathways for Escape using Rationally-Designed Anti-HIV-1 Antibodies

Summary for 4JKP

• Entry DOI: 10.2210/pdb4jkp/pdb
• Descriptor: gp120, Heavy chain of antibody 45-46M2, Light chain of antibody 45-46M2, ... (8 entities in total)
• Functional Keywords: igg, antibody, gp120, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1 (HIV); More
• Total number of polymer chains: 3
• Total formula weight: 92175.91

Authors

Diskin, R.,Bjorkman, P.J. (deposition date: 2013-03-11, release date: 2013-05-15, Last modification date: 2020-07-29)

• Primary citation: Diskin, R.,Klein, F.,Horwitz, J.A.,Halper-Stromberg, A.,Sather, D.N.,Marcovecchio, P.M.,Lee, T.,West, A.P.,Gao, H.,Seaman, M.S.,Stamatatos, L.,Nussenzweig, M.C.,Bjorkman, P.J.; Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies.; J.Exp.Med., 210:1235-1249, 2013; PubMed: 23712429; DOI: 10.1084/jem.20130221

Experimental method

X-RAY DIFFRACTION (2.82 Å)