4JKP
Restricting HIV-1 Pathways for Escape using Rationally-Designed Anti-HIV-1 Antibodies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | gp120 | polymer | 361 | 40204.5 | 1 | Pfam (PF00516) UniProt (by SIFTS) (Q0ED31) | Human immunodeficiency virus 1 (HIV) | |
| 2 | B (H) | Heavy chain of antibody 45-46M2 | polymer | 229 | 25218.5 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | Light chain of antibody 45-46M2 | polymer | 210 | 23076.5 | 1 | Homo sapiens (human) | ||
| 4 | D (A) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G34442SS) | |||
| 5 | E (B) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 6 | F (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 7 | G, H, I, J, K (G, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 8 | L, M, N (G, H, L) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 88499.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2570.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 92175.9 |
