6XJD

Two mouse cGAS catalytic domain binding to human assembled nucleosome

Summary for 6XJD

• Entry DOI: 10.2210/pdb6xjd/pdb
• EMDB information: 22046 22206
• Descriptor: Histone H3.2, Histone H4, Histone H2A type 1, ... (8 entities in total)
• Functional Keywords: immunity, immune system, immune system-dna complex, immune system/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 286790.11

Authors

Xu, P.,Li, P.,Zhao, B. (deposition date: 2020-06-23, release date: 2020-09-16, Last modification date: 2024-03-06)

• Primary citation: Zhao, B.,Xu, P.,Rowlett, C.M.,Jing, T.,Shinde, O.,Lei, Y.,West, A.P.,Liu, W.R.,Li, P.; The molecular basis of tight nuclear tethering and inactivation of cGAS.; Nature, 587:673-677, 2020; PubMed: 32911481; DOI: 10.1038/s41586-020-2749-z

Experimental method

ELECTRON MICROSCOPY (6.8 Å)