6XJD
Two mouse cGAS catalytic domain binding to human assembled nucleosome
Summary for 6XJD
Entry DOI | 10.2210/pdb6xjd/pdb |
EMDB information | 22046 22206 |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (8 entities in total) |
Functional Keywords | immunity, immune system, immune system-dna complex, immune system/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 286790.11 |
Authors | |
Primary citation | Zhao, B.,Xu, P.,Rowlett, C.M.,Jing, T.,Shinde, O.,Lei, Y.,West, A.P.,Liu, W.R.,Li, P. The molecular basis of tight nuclear tethering and inactivation of cGAS. Nature, 587:673-677, 2020 Cited by PubMed: 32911481DOI: 10.1038/s41586-020-2749-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.8 Å) |
Structure validation
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