3QAH
 
 | | Crystal structure of apo-form human MOF catalytic domain | | 分子名称: | Probable histone acetyltransferase MYST1, ZINC ION | | 著者 | Sun, B, Tang, Q, Zhong, C, Ding, J. | | 登録日 | 2011-01-11 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274
Cell Res., 21, 2011
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3RPN
 | | Crystal structure of human kappa class glutathione transferase in complex with S-hexylglutathione | | 分子名称: | Glutathione S-transferase kappa 1, S-HEXYLGLUTATHIONE | | 著者 | Wang, B, Peng, Y, Zhang, T, Ding, J. | | 登録日 | 2011-04-27 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism.
Biochem.J., 439, 2011
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3RIB
 | | Human lysine methyltransferase Smyd2 in complex with AdoHcy | | 分子名称: | N-lysine methyltransferase SMYD2, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | 著者 | Xu, S, Zhang, T, Zhong, C, Ding, J. | | 登録日 | 2011-04-13 | | 公開日 | 2011-07-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins
J Mol Cell Biol, 3, 2011
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3RPP
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3SP4
 | | Crystal structure of aprataxin ortholog Hnt3 from Schizosaccharomyces pombe | | 分子名称: | Aprataxin-like protein, SULFATE ION, ZINC ION | | 著者 | Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D. | | 登録日 | 2011-07-01 | | 公開日 | 2011-10-12 | | 最終更新日 | 2013-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
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3SPL
 | | Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin-like protein, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), ... | | 著者 | Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D. | | 登録日 | 2011-07-02 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
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3SPD
 | | Crystal structure of aprataxin ortholog Hnt3 in complex with DNA | | 分子名称: | Aprataxin-like protein, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), DNA (5'-D(*TP*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*AP*C)-3'), ... | | 著者 | Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D. | | 登録日 | 2011-07-01 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.912 Å) | | 主引用文献 | Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
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4HKA
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7VKR
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7VKK
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7VKQ
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2K3C
 | | Structural and Functional Characterization of TM IX of the NHE1 Isoform of the Na+/H+ Exchanger | | 分子名称: | TMIX peptide | | 著者 | Reddy, T, Ding, J, Li, X, Sykes, B.D, Fliegel, L, Rainey, J.K. | | 登録日 | 2008-05-01 | | 公開日 | 2008-06-03 | | 最終更新日 | 2020-02-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger.
J.Biol.Chem., 283, 2008
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1T03
 | | HIV-1 reverse transcriptase crosslinked to tenofovir terminated template-primer (complex P) | | 分子名称: | MAGNESIUM ION, POL polyprotein, Synthetic oligonucleotide primer, ... | | 著者 | Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E. | | 登録日 | 2004-04-07 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
Nat.Struct.Mol.Biol., 11, 2004
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1T05
 | | HIV-1 reverse transcriptase crosslinked to template-primer with tenofovir-diphosphate bound as the incoming nucleotide substrate | | 分子名称: | GLYCEROL, MAGNESIUM ION, POL polyprotein, ... | | 著者 | Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E. | | 登録日 | 2004-04-07 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
Nat.Struct.Mol.Biol., 11, 2004
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8GRG
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8GRU
 | | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca | | 分子名称: | CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ... | | 著者 | Sun, P, Chen, X, Ding, J. | | 登録日 | 2022-09-02 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.847 Å) | | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
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8GS5
 | | Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form | | 分子名称: | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ... | | 著者 | Sun, P, Chen, X, Ding, J. | | 登録日 | 2022-09-04 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4.486 Å) | | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
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8GRB
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8GRH
 | | Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT | | 分子名称: | CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ... | | 著者 | Sun, P, Chen, X, Ding, J. | | 登録日 | 2022-09-01 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
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8GRD
 | | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ... | | 著者 | Chen, X, Sun, P, Ding, J. | | 登録日 | 2022-09-01 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
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8H68
 | | Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Shi, Y, Ding, J, Yang, H. | | 登録日 | 2022-10-16 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Caenorhabditis elegans NMAD-1 functions as a demethylase for actin.
J Mol Cell Biol, 15, 2023
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7VUX
 | | Complex structure of PD1 and 609A-Fab | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Huang, H, Zhu, Z, Zhao, J, Jiang, L, Yang, H, Deng, L, Meng, X, Ding, J, Yang, S, Zhao, L, Xu, W, Wang, X. | | 登録日 | 2021-11-04 | | 公開日 | 2021-11-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties.
Mabs, 14, 2022
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8J6K
 | | Crystal structure of pro-interleukin-18 and caspase-4 complex | | 分子名称: | Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ... | | 著者 | Sun, Q, Hou, Y.J, Ding, J. | | 登録日 | 2023-04-26 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.
Nature, 624, 2023
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8JKN
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8JKQ
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