7VKK

Crystal structure of D. melanogaster SAMTOR V66W/E67P mutant

Summary for 7VKK

Entry DOI	10.2210/pdb7vkk/pdb
Descriptor	S-adenosylmethionine sensor upstream of mTORC1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION (3 entities in total)
Functional Keywords	samtor, transferase, sam
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	2
Total formula weight	70640.88
Authors	Zhang, T.,Ding, J. (deposition date: 2021-09-30, release date: 2022-07-20, Last modification date: 2023-11-29)
Primary citation	Tang, X.,Zhang, Y.,Wang, G.,Zhang, C.,Wang, F.,Shi, J.,Zhang, T.,Ding, J. Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling. Sci Adv, 8:eabn3868-eabn3868, 2022 Cited by PubMed: 35776786 DOI: 10.1126/sciadv.abn3868 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.55 Å)

Structure validation