8JKN

T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAAA motif

Summary for 8JKN

• Entry DOI: 10.2210/pdb8jkn/pdb
• Descriptor: GAAA-Forward, GAAA-Reverse, Interferon regulatory factor 4, ... (4 entities in total)
• Functional Keywords: irf4, transcription factor, protein-dna complex, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 77885.10

Authors

Wang, G.,Feng, X.,Ding, J. (deposition date: 2023-06-01, release date: 2023-09-20, Last modification date: 2023-11-15)

• Primary citation: Wang, G.,Feng, X.,Ding, J.; Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.; Structure, 31:1441-, 2023; PubMed: 37683642; DOI: 10.1016/j.str.2023.08.013

Experimental method

X-RAY DIFFRACTION (2.92 Å)