4HKA

Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase in complex with HEME

Summary for 4HKA

Entry DOI	10.2210/pdb4hka/pdb
Descriptor	Tryptophan 2,3-dioxygenase, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	kynurenine pathway, catalytic mechanism, regulatory mechanism, oxidoreductase
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	1
Total formula weight	43978.21
Authors	Huang, W.,Ding, J. (deposition date: 2012-10-15, release date: 2013-03-27, Last modification date: 2024-02-28)
Primary citation	Huang, W.,Gong, Z.,Li, J.,Ding, J. Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase reveals insights into substrate recognition and catalytic mechanism. J.Struct.Biol., 181:291-299, 2013 Cited by PubMed: 23333332 DOI: 10.1016/j.jsb.2013.01.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation