7VUX

Complex structure of PD1 and 609A-Fab

Summary for 7VUX

• Entry DOI: 10.2210/pdb7vux/pdb
• Descriptor: Programmed cell death protein 1, Heavy chain of Fab fragment, Light chain of Fab fragment, ... (10 entities in total)
• Functional Keywords: pd1 fab complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 63178.27

Authors

Huang, H.,Zhu, Z.,Zhao, J.,Jiang, L.,Yang, H.,Deng, L.,Meng, X.,Ding, J.,Yang, S.,Zhao, L.,Xu, W.,Wang, X. (deposition date: 2021-11-04, release date: 2021-11-17, Last modification date: 2023-11-29)

• Primary citation: Zhao, J.,Jiang, L.,Yang, H.,Deng, L.,Meng, X.,Ding, J.,Yang, S.,Zhao, L.,Xu, W.,Wang, X.,Zhu, Z.,Huang, H.; A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties.; Mabs, 14:2044435-2044435, 2022; PubMed: 35239451; DOI: 10.1080/19420862.2022.2044435

Experimental method

X-RAY DIFFRACTION (1.64 Å)