7VUX
Complex structure of PD1 and 609A-Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Programmed cell death protein 1 | polymer | 136 | 15313.1 | 1 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (Human) | Protein PD-1,hPD-1 |
| 2 | B (H) | Heavy chain of Fab fragment | polymer | 216 | 23037.7 | 1 | Homo sapiens | ||
| 3 | C (L) | Light chain of Fab fragment | polymer | 214 | 23439.0 | 1 | Homo sapiens | ||
| 4 | D (A) | THREONINE | non-polymer | 119.1 | 1 | Chemie (THR) | |||
| 5 | E, F, I, J, O... (A, H, L) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 6 | G, K, L, M, N... (A, H, L) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 7 | H, U (H, L) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | P (L) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 9 | V (L) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 10 | W, X, Y (A, H, L) | water | water | 18.0 | 789 | Chemie (HOH) |
Sequence modifications
A: 32 - 160 (UniProt: Q15116)
| PDB | External Database | Details |
|---|---|---|
| Met 31 | - | initiating methionine |
| Ser 93 | Cys 93 | conflict |
| Glu 161 | - | expression tag |
| Asn 162 | - | expression tag |
| Leu 163 | - | expression tag |
| Tyr 164 | - | expression tag |
| Phe 165 | - | expression tag |
| Gln 166 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61789.8 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1388.4 | |
| All* | Total formula weight | 63178.3 |
