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7LUD
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BU of 7lud by Molmil
Crystal structure of Fab ADI-14442
Descriptor: ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION
Authors:Rush, S.A, McLellan, J.S.
Deposit date:2021-02-22
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7M1C
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BU of 7m1c by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-32
Descriptor: 1-32 Fab Heavy Chain, 1-32 Fab Light Chain
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-03-12
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M30
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BU of 7m30 by Molmil
Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25
Descriptor: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain, 1-32 Fab Heavy Chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-03-17
Release date:2021-08-11
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYV
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BU of 7lyv by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-103
Descriptor: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain
Authors:Wrapp, D, Jones, H.G, McLellan, J.S.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M22
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BU of 7m22 by Molmil
Cryo-EM structure of the HCMV pentamer bound by human neuropilin 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein UL130, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-03-15
Release date:2021-08-11
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYW
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BU of 7lyw by Molmil
Crystal structure of the HCMV pentamer-specific antibody 2-25
Descriptor: 2-25 Fab Heavy Chain, 2-25 Fab Light Chain
Authors:Wrapp, D, Mishra, A.K, McLellan, J.S.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M8J
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BU of 7m8j by Molmil
SARS-CoV-2 S-NTD + Fab CM25
Descriptor: CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1
Authors:Johnson, N.V, Mclellan, J.S.
Deposit date:2021-03-29
Release date:2021-05-19
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
Science, 372, 2021
7LUE
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BU of 7lue by Molmil
Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442
Descriptor: Fusion glycoprotein F0, Heavy chain of human antibody Fab ADI-14442, Light chain of human antibody Fab ADI-14442
Authors:Gilman, M.S.A, McLellan, J.S.
Deposit date:2021-02-22
Release date:2021-06-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7LUC
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BU of 7luc by Molmil
Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B
Descriptor: 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-02-22
Release date:2021-04-21
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
8TCO
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BU of 8tco by Molmil
HCMV Trimer in complex with CS2it1p2_F7K Fab and CS4tt1p1_E3K Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CS2it1p2_F7K Fab heavy chain, ...
Authors:Goldsmith, J.G, McLellan, J.S.
Deposit date:2023-07-02
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:HCMV neutralization by broad antibody targeting
To Be Published
8TEA
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BU of 8tea by Molmil
HCMV Pentamer in complex with CS2pt1p2_A10L Fab and CS3pt1p4_C1L Fab
Descriptor: CS2pt1p2_A10L Fab heavy chain, CS2pt1p2_A10L Fab light chain, CS3pt1p4_C1L Fab heavy chain, ...
Authors:Goldsmith, J.G, McLellan, J.S.
Deposit date:2023-07-05
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:HCMV neutralization by broad antibody targeting
To Be Published
7S3N
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BU of 7s3n by Molmil
SARS-CoV-2 S stem helix peptide bound to Fab22
Descriptor: Fab22 Heavy Chain, Fab22 Light Chain, Spike glycoprotein
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Stabilized coronavirus spike stem elicits a broadly protective antibody.
Cell Rep, 37, 2021
7SSC
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BU of 7ssc by Molmil
TRL345 lineage ancestor I8 Fab bound to an HCMV gB-derived peptide
Descriptor: Envelope glycoprotein B peptide, GLYCEROL, TRL345-I8 Fab heavy chain, ...
Authors:Sponholtz, M.R, McLellan, J.S.
Deposit date:2021-11-10
Release date:2022-10-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus.
Plos Pathog., 19, 2023
7SEJ
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BU of 7sej by Molmil
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 subunit, Fusion glycoprotein F2 subunit
Authors:Hsieh, C.-L, Rush, S.A, McLellan, J.S.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
7SEM
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BU of 7sem by Molmil
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
Authors:Rush, S.A, Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-09-30
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
7T01
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BU of 7t01 by Molmil
SARS-CoV-2 S-RBD + Fab 54042-4
Descriptor: 54042-4 Fab - Heavy Chain, 54042-4 Fab - Light Chain, Spike protein S1
Authors:Johnson, N.V, Mclellan, J.S.
Deposit date:2021-11-29
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition.
Cell Rep, 37, 2021
7SJ0
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BU of 7sj0 by Molmil
Antibody A7V3 bound to N-terminal domain of the spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, A7V3 Fab heavy chain, A7V3 Fab light chain, ...
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-10-15
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Antibody A7V3 bound to N-terminal domain of the spike
To Be Published
7T67
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BU of 7t67 by Molmil
SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2021-12-13
Release date:2022-08-24
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Nat Commun, 13, 2022
7T3M
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BU of 7t3m by Molmil
SARS-CoV-2 S (Spike Glycoprotein) D614G with Three (3) RBDs Up, Bound to Antibody 2-7 scFv, composite map
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2-7 scFv, ...
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2021-12-08
Release date:2022-08-24
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Nat Commun, 13, 2022
7TJQ
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BU of 7tjq by Molmil
SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
Authors:Hsieh, C.-L, McLellan, J.S, Rush, S.A.
Deposit date:2022-01-16
Release date:2022-09-14
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7TL0
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BU of 7tl0 by Molmil
Cryo-EM structure of hMPV preF bound by Fabs MPE8 and SAN32-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
Authors:Rush, S.A, Hsieh, C.-L, McLellan, J.S.
Deposit date:2022-01-17
Release date:2022-09-14
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7RAH
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BU of 7rah by Molmil
Adenylate cyclase toxin RTX domain fragment bound to M1H5 Fab and M2B10 Fab
Descriptor: Bifunctional adenylate cyclase toxin/hemolysin CyaA,Bifunctional adenylate cyclase toxin/hemolysin CyaA, CALCIUM ION, M1H5 Fab Heavy Chain, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2021-07-01
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes.
Plos Pathog., 17, 2021
7RW6
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BU of 7rw6 by Molmil
BORF2-APOBEC3Bctd Complex
Descriptor: DNA dC->dU-editing enzyme APOBEC-3B, Maltose/maltodextrin-binding periplasmic protein,Ribonucleoside-diphosphate reductase large subunit, ZINC ION
Authors:Shaban, N.M, Yan, R, Shi, K, McLellan, J.S, Yu, Z, Harris, R.S.
Deposit date:2021-08-19
Release date:2022-04-27
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.
Sci Adv, 8, 2022
7S3M
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BU of 7s3m by Molmil
MERS-CoV S stem helix peptide bound to Fab22
Descriptor: Fab22 Heavy Chain, Fab22 Light Chain, Spike glycoprotein
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Stabilized coronavirus spike stem elicits a broadly protective antibody.
Cell Rep, 37, 2021
5I08
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BU of 5i08 by Molmil
Prefusion structure of a human coronavirus spike protein
Descriptor: Spike glycoprotein,Foldon chimera
Authors:Kirchdoerfer, R.N, Cottrell, C.A, Wang, N, Pallesen, J, Yassine, H.M, Turner, H.L, Corbett, K.S, Graham, B.S, McLellan, J.S, Ward, A.B.
Deposit date:2016-02-03
Release date:2016-03-02
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Pre-fusion structure of a human coronavirus spike protein.
Nature, 531, 2016

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