7LUE
Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442
Summary for 7LUE
Entry DOI | 10.2210/pdb7lue/pdb |
EMDB information | 23521 |
Descriptor | Fusion glycoprotein F0, Heavy chain of human antibody Fab ADI-14442, Light chain of human antibody Fab ADI-14442 (3 entities in total) |
Functional Keywords | fusion, immunoglobulin, public clonotype, convergent recognition, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Respiratory syncytial virus A2 More |
Total number of polymer chains | 9 |
Total formula weight | 327117.33 |
Authors | |
Primary citation | Mukhamedova, M.,Wrapp, D.,Shen, C.H.,Gilman, M.S.A.,Ruckwardt, T.J.,Schramm, C.A.,Ault, L.,Chang, L.,Derrien-Colemyn, A.,Lucas, S.A.M.,Ransier, A.,Darko, S.,Phung, E.,Wang, L.,Zhang, Y.,Rush, S.A.,Madan, B.,Stewart-Jones, G.B.E.,Costner, P.J.,Holman, L.A.,Hickman, S.P.,Berkowitz, N.M.,Doria-Rose, N.A.,Morabito, K.M.,DeKosky, B.J.,Gaudinski, M.R.,Chen, G.L.,Crank, M.C.,Misasi, J.,Sullivan, N.J.,Douek, D.C.,Kwong, P.D.,Graham, B.S.,McLellan, J.S.,Mascola, J.R. Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54:769-780.e6, 2021 Cited by PubMed: 33823129DOI: 10.1016/j.immuni.2021.03.004 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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