7LUE
Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Fusion glycoprotein F0 | polymer | 548 | 61132.7 | 3 | UniProt (W8RJF9) UniProt (by SIFTS) (P03420) | Respiratory syncytial virus A2 | Fusion glycoprotein F1,Fusion glycoprotein F2 |
| 2 | D, E, F (H, I, J) | Heavy chain of human antibody Fab ADI-14442 | polymer | 225 | 23805.6 | 3 | Homo sapiens (Human) | ||
| 3 | G, H, I (L, M, N) | Light chain of human antibody Fab ADI-14442 | polymer | 219 | 24100.8 | 3 | Homo sapiens (Human) |
Sequence modifications
A, B, C: 26 - 513 (UniProt: W8RJF9)
| PDB | External Database | Details |
|---|---|---|
| Glu 66 | Lys 66 | conflict |
| Ile 67 | Asn 67 | engineered mutation |
| Pro 215 | Ser 215 | engineered mutation |
| Ser 514 | - | expression tag |
| Ala 515 | - | expression tag |
| Ile 516 | - | expression tag |
| Gly 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Tyr 519 | - | expression tag |
| Ile 520 | - | expression tag |
| Pro 521 | - | expression tag |
| Glu 522 | - | expression tag |
| Ala 523 | - | expression tag |
| Pro 524 | - | expression tag |
| Arg 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Gly 527 | - | expression tag |
| Gln 528 | - | expression tag |
| Ala 529 | - | expression tag |
| Tyr 530 | - | expression tag |
| Val 531 | - | expression tag |
| Arg 532 | - | expression tag |
| Lys 533 | - | expression tag |
| Asp 534 | - | expression tag |
| Gly 535 | - | expression tag |
| Glu 536 | - | expression tag |
| Trp 537 | - | expression tag |
| Val 538 | - | expression tag |
| Leu 539 | - | expression tag |
| Leu 540 | - | expression tag |
| Ser 541 | - | expression tag |
| Thr 542 | - | expression tag |
| Phe 543 | - | expression tag |
| Leu 544 | - | expression tag |
| Gly 545 | - | expression tag |
| Ser 546 | - | expression tag |
| Leu 547 | - | expression tag |
| Glu 548 | - | expression tag |
| Val 549 | - | expression tag |
| Leu 550 | - | expression tag |
| Phe 551 | - | expression tag |
| Gln 552 | - | expression tag |
| Gly 553 | - | expression tag |
| Pro 554 | - | expression tag |
| Gly 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
| His 559 | - | expression tag |
| His 560 | - | expression tag |
| His 561 | - | expression tag |
| His 562 | - | expression tag |
| His 563 | - | expression tag |
| Ser 564 | - | expression tag |
| Ala 565 | - | expression tag |
| Trp 566 | - | expression tag |
| Ser 567 | - | expression tag |
| His 568 | - | expression tag |
| Pro 569 | - | expression tag |
| Gln 570 | - | expression tag |
| Phe 571 | - | expression tag |
| Glu 572 | - | expression tag |
| Lys 573 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 327117.3 | |
| All* | Total formula weight | 327117.3 |
