7TL0

Cryo-EM structure of hMPV preF bound by Fabs MPE8 and SAN32-2

Summary for 7TL0

Entry DOI	10.2210/pdb7tl0/pdb
Related	7TJQ
EMDB information	25929 25982
Descriptor	Fusion glycoprotein F0, SAN32-2 Fab heavy chain, SAN32-2 Fab light chain, ... (7 entities in total)
Functional Keywords	neutralizing antibody, fusion protein, metapneumovirus, site 0, viral protein-immune system complex, viral protein/immune system
Biological source	Human metapneumovirus More
Total number of polymer chains	15
Total formula weight	467161.72
Authors	Rush, S.A.,Hsieh, C.-L.,McLellan, J.S. (deposition date: 2022-01-17, release date: 2022-09-14, Last modification date: 2022-11-23)
Primary citation	Rush, S.A.,Brar, G.,Hsieh, C.L.,Chautard, E.,Rainho-Tomko, J.N.,Slade, C.D.,Bricault, C.A.,Kume, A.,Kearns, J.,Groppo, R.,Mundle, S.T.,Zhang, L.,Casimiro, D.,Fu, T.M.,DiNapoli, J.M.,McLellan, J.S. Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus. Cell Rep, 40:111399-111399, 2022 Cited by PubMed: 36130517 DOI: 10.1016/j.celrep.2022.111399 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.06 Å)

Structure validation