7SSC

TRL345 lineage ancestor I8 Fab bound to an HCMV gB-derived peptide

Summary for 7SSC

• Entry DOI: 10.2210/pdb7ssc/pdb
• Descriptor: TRL345-I8 Fab heavy chain, TRL345-I8 Fab light chain, Envelope glycoprotein B peptide, ... (5 entities in total)
• Functional Keywords: immunoglobulin, fusion protein, hcmv, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 48760.24

Authors

Sponholtz, M.R.,McLellan, J.S. (deposition date: 2021-11-10, release date: 2022-10-19, Last modification date: 2023-10-25)

• Primary citation: Jenks, J.A.,Amin, S.,Sponholtz, M.R.,Kumar, A.,Wrapp, D.,Venkatayogi, S.,Tu, J.J.,Karthigeyan, K.,Valencia, S.M.,Connors, M.,Harnois, M.J.,Hora, B.,Rochat, E.,McLellan, J.S.,Wiehe, K.,Permar, S.R.; A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus.; Plos Pathog., 19:e1011107-e1011107, 2023; PubMed: 36662906; DOI: 10.1371/journal.ppat.1011107

Experimental method

X-RAY DIFFRACTION (1.8 Å)