7M30
Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25
Summary for 7M30
Entry DOI | 10.2210/pdb7m30/pdb |
EMDB information | 23640 |
Descriptor | Envelope glycoprotein L, 1-103 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | hcmv pentamer, fab, cytomegalovirus, immunocomplex, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human cytomegalovirus (HHV-5, Human herpesvirus 5) More |
Total number of polymer chains | 10 |
Total formula weight | 224409.68 |
Authors | Wrapp, D.,McLellan, J.S. (deposition date: 2021-03-17, release date: 2021-08-11, Last modification date: 2022-03-23) |
Primary citation | Wrapp, D.,Ye, X.,Ku, Z.,Su, H.,Jones, H.G.,Wang, N.,Mishra, A.K.,Freed, D.C.,Li, F.,Tang, A.,Li, L.,Jaijyan, D.K.,Zhu, H.,Wang, D.,Fu, T.M.,Zhang, N.,An, Z.,McLellan, J.S. Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8:eabm2546-eabm2546, 2022 Cited by PubMed: 35275718DOI: 10.1126/sciadv.abm2546 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.81 Å) |
Structure validation
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