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7M30

Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Envelope glycoprotein Lpolymer24827664.61UniProt (P16832)
Pfam (PF01801)
Human cytomegalovirus (HHV-5 Human herpesvirus 5)gL
2B
(C)
Envelope protein UL128polymer14416684.31UniProt (C8BLJ3)
Pfam (PF25700)
UniProt (by SIFTS) (P16837)
Human cytomegalovirus (HHV-5)UL128
3C
(D)
Envelope glycoprotein UL130polymer18921761.71UniProt (A0A0G2TB82)
Pfam (PF11668)
UniProt (by SIFTS) (P16772)
Human cytomegalovirus (HHV-5)ORFL272C_UL130,UL130 protein
4D
(E)
UL131Apolymer11113005.51UniProt (Q38M21)
UniProt (by SIFTS) (F5HET4)
Human cytomegalovirus (HHV-5)
5E
(F)
2-25 Fab Heavy Chainpolymer23425206.31Homo sapiens
6F
(G)
2-25 Fab Light Chainpolymer21222724.01Homo sapiens
7G
(H)
1-32 Fab Heavy Chainpolymer24126082.41Homo sapiens
8H
(L)
1-32 Fab Light Chainpolymer21323319.71Homo sapiens
9I
(M)
1-103 Fab Heavy Chainpolymer23224679.61Homo sapiens
10J
(N)
1-103 Fab Light Chainpolymer21022839.21Homo sapiens
11K, L
(D, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight223967.3
Non-Polymers*Number of molecules2
Total formula weight442.4
All*Total formula weight224409.7
*Water molecules are not included.

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PDB entries from 2026-02-11

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