7TJQ

SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F

Summary for 7TJQ

• Entry DOI: 10.2210/pdb7tjq/pdb
• Related: 7TL0
• EMDB information: 25929 25982
• Descriptor: SAN27-14 Fab heavy chain, SAN27-14 Fab light chain, Fusion glycoprotein F0, ... (6 entities in total)
• Functional Keywords: neutralizing antibodies, prefusion-specific antibodies, antigenic site v, hmpv f, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 15
• Total formula weight: 403422.24

Authors

Hsieh, C.-L.,McLellan, J.S.,Rush, S.A. (deposition date: 2022-01-16, release date: 2022-09-14, Last modification date: 2022-11-23)

• Primary citation: Rush, S.A.,Brar, G.,Hsieh, C.L.,Chautard, E.,Rainho-Tomko, J.N.,Slade, C.D.,Bricault, C.A.,Kume, A.,Kearns, J.,Groppo, R.,Mundle, S.T.,Zhang, L.,Casimiro, D.,Fu, T.M.,DiNapoli, J.M.,McLellan, J.S.; Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.; Cell Rep, 40:111399-111399, 2022; PubMed: 36130517; DOI: 10.1016/j.celrep.2022.111399

Experimental method

ELECTRON MICROSCOPY (3.13 Å)