8TCO

HCMV Trimer in complex with CS2it1p2_F7K Fab and CS4tt1p1_E3K Fab

Summary for 8TCO

• Entry DOI: 10.2210/pdb8tco/pdb
• EMDB information: 41156 41157 41158 41160 41161
• Descriptor: Envelope glycoprotein H, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein L, ... (10 entities in total)
• Functional Keywords: virus, glycoprotein, antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Human betaherpesvirus 5; More
• Total number of polymer chains: 7
• Total formula weight: 269731.10

Authors

Goldsmith, J.A.,McLellan, J.S. (deposition date: 2023-07-02, release date: 2023-08-09, Last modification date: 2024-08-14)

• Primary citation: Zehner, M.,Alt, M.,Ashurov, A.,Goldsmith, J.A.,Spies, R.,Weiler, N.,Lerma, J.,Gieselmann, L.,Stohr, D.,Gruell, H.,Schultz, E.P.,Kreer, C.,Schlachter, L.,Janicki, H.,Laib Sampaio, K.,Stegmann, C.,Nemetchek, M.D.,Dahling, S.,Ullrich, L.,Dittmer, U.,Witzke, O.,Koch, M.,Ryckman, B.J.,Lotfi, R.,McLellan, J.S.,Krawczyk, A.,Sinzger, C.,Klein, F.; Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.; Immunity, 56:2602-2620.e10, 2023; PubMed: 37967532; DOI: 10.1016/j.immuni.2023.10.009

Experimental method

ELECTRON MICROSCOPY (2.8 Å)