8TCO
HCMV Trimer in complex with CS2it1p2_F7K Fab and CS4tt1p1_E3K Fab
Summary for 8TCO
Entry DOI | 10.2210/pdb8tco/pdb |
EMDB information | 41156 41157 41158 41160 41161 |
Descriptor | Envelope glycoprotein H, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein L, ... (10 entities in total) |
Functional Keywords | virus, glycoprotein, antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Human betaherpesvirus 5 More |
Total number of polymer chains | 7 |
Total formula weight | 269731.10 |
Authors | Goldsmith, J.A.,McLellan, J.S. (deposition date: 2023-07-02, release date: 2023-08-09, Last modification date: 2024-08-14) |
Primary citation | Zehner, M.,Alt, M.,Ashurov, A.,Goldsmith, J.A.,Spies, R.,Weiler, N.,Lerma, J.,Gieselmann, L.,Stohr, D.,Gruell, H.,Schultz, E.P.,Kreer, C.,Schlachter, L.,Janicki, H.,Laib Sampaio, K.,Stegmann, C.,Nemetchek, M.D.,Dahling, S.,Ullrich, L.,Dittmer, U.,Witzke, O.,Koch, M.,Ryckman, B.J.,Lotfi, R.,McLellan, J.S.,Krawczyk, A.,Sinzger, C.,Klein, F. Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer. Immunity, 56:2602-2620.e10, 2023 Cited by PubMed: 37967532DOI: 10.1016/j.immuni.2023.10.009 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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