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PDB: 7 results
8TW3
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BU of 8tw3 by Molmil
hMPV fusion protein complexed with single domain antibodies sdHMPV16 and sdHMPV12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein, Single domain antibody sdHMPV12, ...
Authors:Rush, S.A, McLellan, J.S.
Deposit date:2023-08-19
Release date:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein.
Mbio, 15, 2024
7UR4
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BU of 7ur4 by Molmil
Cryo-EM Structure of the Neutralizing Antibody MPV467 in Complex with Prefusion Human Metapneumovirus F Glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPV467 Fab Heavy chain, ...
Authors:Rush, S.A, McLellan, J.S.
Deposit date:2022-04-21
Release date:2022-06-08
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SEM
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BU of 7sem by Molmil
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
Authors:Rush, S.A, Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-09-30
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
7TL0
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BU of 7tl0 by Molmil
Cryo-EM structure of hMPV preF bound by Fabs MPE8 and SAN32-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
Authors:Rush, S.A, Hsieh, C.-L, McLellan, J.S.
Deposit date:2022-01-17
Release date:2022-09-14
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7LUD
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BU of 7lud by Molmil
Crystal structure of Fab ADI-14442
Descriptor: ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION
Authors:Rush, S.A, McLellan, J.S.
Deposit date:2021-02-22
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7SEJ
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BU of 7sej by Molmil
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 subunit, Fusion glycoprotein F2 subunit
Authors:Hsieh, C.-L, Rush, S.A, McLellan, J.S.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
7TJQ
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BU of 7tjq by Molmil
SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
Authors:Hsieh, C.-L, McLellan, J.S, Rush, S.A.
Deposit date:2022-01-16
Release date:2022-09-14
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022

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