8TW3

hMPV fusion protein complexed with single domain antibodies sdHMPV16 and sdHMPV12

Summary for 8TW3

• Entry DOI: 10.2210/pdb8tw3/pdb
• Descriptor: Single domain antibody sdHMPV12, Single domain antibody sdHMPV16, Fusion glycoprotein, ... (4 entities in total)
• Functional Keywords: metapneumovirus, fusion protein, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Lama glama (llama); More
• Total number of polymer chains: 6
• Total formula weight: 201491.20

Authors

Rush, S.A.,McLellan, J.S. (deposition date: 2023-08-19, release date: 2024-01-24)

• Primary citation: Ballegeer, M.,van Scherpenzeel, R.C.,Delgado, T.,Iglesias-Caballero, M.,Garcia Barreno, B.,Pandey, S.,Rush, S.A.,Kolkman, J.A.,Mas, V.,McLellan, J.S.,Saelens, X.; A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein.; Mbio, 15:e0212223-e0212223, 2024; PubMed: 38117059; DOI: 10.1128/mbio.02122-23

Experimental method

X-RAY DIFFRACTION (2.9 Å)