5IT7
| Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2 | Descriptor: | (2S)-1-amino-N,N,N-trimethyl-1-oxobutan-2-aminium, 18S ribosomal RNA, 25S ribosomal RNA, ... | Authors: | Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. | Deposit date: | 2016-03-16 | Release date: | 2016-05-18 | Last modified: | 2018-11-21 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016
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4KHP
| Structure of the Thermus thermophilus 30S ribosomal subunit in complex with de-6-MSA-pactamycin | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal protein S10, 30S Ribosomal protein S11, ... | Authors: | Tourigny, D.S, Fernandez, I.S, Kelley, A.C, Ramakrishnan, V. | Deposit date: | 2013-05-01 | Release date: | 2013-06-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit. J.Mol.Biol., 425, 2013
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4LD9
| Crystal structure of the N-terminally acetylated BAH domain of Sir3 bound to the nucleosome core particle | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3.2, ... | Authors: | Arnaudo, N, Fernandez, I.S, McLaughlin, S.H, Peak-Chew, S.Y, Rhodes, D, Martino, F. | Deposit date: | 2013-06-24 | Release date: | 2013-08-14 | Last modified: | 2013-09-18 | Method: | X-RAY DIFFRACTION (3.306 Å) | Cite: | The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle. Nat.Struct.Mol.Biol., 20, 2013
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7RZY
| CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC) | Authors: | Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2021-08-28 | Release date: | 2022-06-08 | Last modified: | 2022-09-21 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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3J7R
| Structure of the translating mammalian ribosome-Sec61 complex | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2019-10-30 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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3J7O
| Structure of the mammalian 60S ribosomal subunit | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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3J7A
| Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... | Authors: | Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. | Deposit date: | 2014-06-03 | Release date: | 2014-07-16 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
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3J81
| CryoEM structure of a partial yeast 48S preinitiation complex | Descriptor: | 18S rRNA, MAGNESIUM ION, METHIONINE, ... | Authors: | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | Deposit date: | 2014-08-29 | Release date: | 2014-11-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
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3J7Q
| Structure of the idle mammalian ribosome-Sec61 complex | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2019-10-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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3J79
| Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. | Deposit date: | 2014-06-02 | Release date: | 2014-07-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
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3J7P
| Structure of the 80S mammalian ribosome bound to eEF2 | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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3J80
| CryoEM structure of 40S-eIF1-eIF1A preinitiation complex | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | Authors: | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | Deposit date: | 2014-08-28 | Release date: | 2014-11-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
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6P5J
| Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-30 | Release date: | 2019-09-18 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P4H
| Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 2) | Descriptor: | 18S rRNA, IAPV-IRES, RACK1, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-27 | Release date: | 2019-09-18 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P5I
| Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-30 | Release date: | 2019-09-18 | Last modified: | 2020-02-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P4G
| Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | Descriptor: | 18S rRNA, IAPV-IRES, RACK1, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-27 | Release date: | 2019-09-18 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P5N
| Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1 | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-30 | Release date: | 2019-09-25 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P5K
| Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-30 | Release date: | 2019-09-18 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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5UMD
| Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Wong, W, Bai, X.-C, Brown, A, Scheres, S, Baum, J. | Deposit date: | 2017-01-27 | Release date: | 2017-03-01 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis. Nat Microbiol, 2, 2017
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5OC1
| Crystal structure of aryl-alcohol oxidase from Pleurotus eryngii in complex with p-anisic acid | Descriptor: | 4-METHOXYBENZOIC ACID, Aryl-alcohol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Carro, J, Martinez-Julvez, M, Medina, M, Martinez, A, Ferreira, P. | Deposit date: | 2017-06-29 | Release date: | 2017-11-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Protein dynamics promote hydride tunnelling in substrate oxidation by aryl-alcohol oxidase. Phys Chem Chem Phys, 19, 2017
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6OKK
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6PIG
| V. cholerae TniQ-Cascade complex, closed conformation | Descriptor: | RNA (60-MER), TniQ monomer 1, TniQ monomer 2, ... | Authors: | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | Deposit date: | 2019-06-26 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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6PIJ
| Target DNA-bound V. cholerae TniQ-Cascade complex, closed conformation | Descriptor: | Non-targeting strand ssDNA, Targeting strand ssDNA, TniQ monomer 2, ... | Authors: | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | Deposit date: | 2019-06-26 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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6PIF
| V. cholerae TniQ-Cascade complex, open conformation | Descriptor: | Cas7, type I-F CRISPR-associated protein, TniQ monomer 1, ... | Authors: | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | Deposit date: | 2019-06-26 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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3JBO
| Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P/E-tRNA | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... | Authors: | Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. | Deposit date: | 2015-09-16 | Release date: | 2015-10-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res., 43, 2015
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