Structure of the idle mammalian ribosome-Sec61 complex

This is a large structure.
Replaces:  3J72

Summary for 3J7Q

Related3J7O 3J7P 3J7R
Integrates4W24 4W25
EMDB informationEMD-2644 EMD-2646 EMD-2649 EMD-2650
Descriptor28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... (50 entities in total)
Functional Keywordsmammalian, sec61, translocation, translation, ribosome
Biological sourceSus scrofa (pig)
Cellular locationNucleus, nucleolus  
Ubiquitin: Cytoplasm . 60S ribosomal protein L40: Cytoplasm  
Total number of polymer chains48
Total molecular weight2172558.83
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.W.,Hegde, R.S. (deposition date: 2014-08-01, release date: 2014-09-03, Last modification date: 2014-12-17)
Primary citation
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.,Hegde, R.S.
Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157:1632-1643, 2014
PubMed: 24930395 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2014.05.024
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone564.2%20.9%0.28MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j7q
no rotation
Molmil generated image of 3j7q
rotated about x axis by 90°
Molmil generated image of 3j7q
rotated about y axis by 90°
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